Project description:Prognostic Value of Gut Microbiome for Conversion from Mild Cognitive Impairment to Alzheimer’s Disease Dementia within 4 Years: Results from the AlzBiom Study
Project description:Plasma EV proteomic profiling from patients with typical PD combined with different degrees of cognitive impairments (PD with Dementia, PD with mild cognitive impairment, and PD with normal cognition), atypical Parkinsonism represented by Multiple System Atrophy, and healthy individuals
Project description:Alzheimer case-control samples originate from the EU funded AddNeuroMed Cohort, which is a large cross-European AD biomarker study relying on human blood as the source of RNA. The design is case-control. Cases are either Alzheimer's disease patients, subjects with mild cognitive impairment or age and gender matched controls.
Project description:Total RNA sequencing of cultured OM cells derived from patients with Alzheimer's disease (AD), individuals with mild cognitive impairment (MCI) and cognitively healthy controls.
Project description:we investigated tear fluid as a novel source of disease-specific protein biomarkers for Alzheimer disease (AD) development using samples from patients suffering from mild cognitive impairment (MCI) and AD. Tear protein content was evaluated via liquid chromatography–mass spectrometry.
Project description:We have generated human olfactory neurosphere-derived (ONS) cells from individuals with AD or mild cognitive impairment (MCI), and their cognitively healthy controls, and performed global RNA sequencing to determine gene expression changes in ONS cells.
Project description:Control ChIP-seq on middle frontal area 46 tissue female adult (88 years) with mild cognitive impairment For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
Project description:CTCF ChIP-seq on middle frontal area 46 tissue female adult (88 years) with mild cognitive impairment For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
Project description:H3K4me3 ChIP-seq on middle frontal area 46 tissue female adult (88 years) with mild cognitive impairment For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf