Project description:Drug resistance is one of the major challenges in colorectal cancer (CRC) treatment. Overcoming drug resistance and improving the treatment effect of CRC patients who have developed drug resistance is a crucial issue. Crassocephalum rabens and Bidens pilosa are edible plants that are also commonly used as a folk medicine. This study explored the pharmacological mechanism and therapeutic efficacy of bioactive compounds isolated from Crassocephalum rabens and Bidens pilosa for treating drug-resistant CRC in vitro and in vivo.
