Project description:Global warming has become a critical challenge to food safety, causing severe yield losses of major crops worldwide. Here, we report that the endophytic bacterium Enterobacter sp. SA187 induces thermotolerance of crops in a sustainable manner. Microbiome diversity of wheat plants is positively influenced by SA187 in open field agriculture, indicating that beneficial microbes can be a powerful tool to enhance agriculture in open field agriculture.
Project description:Phosphite (Phi) is widely used in agriculture due to its biostimulant effects on plants and its ability to control various phytopathogens. However, its impact on beneficial soil microorganisms remains poorly understood. In this study, we evaluated the effect of Phi on the growth and transcriptional response of the beneficial fungus Trichoderma atroviride. Our results show that low concentrations of Phi, in the presence of phosphate (Pi), promote the growth of T. atroviride, whereas higher concentrations inhibit its development. Transcriptomic analysis via RNA-Seq revealed the activation of genes associated with growth, amino acid biosynthesis, and siderophore transport. Furthermore, Phi enhanced the antagonistic capacity of T. atroviride against Rhizoctonia solani. These findings reveal a novel role of Phi in stimulating beneficial fungi and suggest its combined use with T. atroviride as a sustainable strategy for phytopathogen biocontrol in agricultural systems.
Project description:This study identifies key microbiome and epithelial cell subtypes involved in grass digestion and VFA metabolism in the rumen. By integrating multi-omic data, we reveal novel links between microbial activity, epithelial cell function, and grassland foraging, providing critical insights into mechanisms underlying grass prevalence and their implications for optimizing ruminant health and productivity. This research enhances our understanding of the grass-microbiome- rumen axis and its role in sustainable grazing systems.
Project description:The oomycete Pythium oligandrum is a potential biocontrol agent to control a wide range of fungal and oomycetes-caused diseases such as Pythium myriotylum-caused rhizome rot in ginger leading to reduced yields and compromised quality. Previously, P. oligandrum has been studied for its plant growth-promoting potential by auxin production and induction of disease resistance by elicitors such as oligandrin. Volatile organic compounds (VOCs) play beneficial roles in sustainable agriculture by enhancing plant growth and resistance. We investigated the contribution of P. oligandrum-produced VOCs on plant growth and disease suppression by initially using N. benthamiana plants for screening. P. oligandrum VOCs significantly enhanced tobacco seedling and plant biomass content. Screening of the individual VOCs showed that 3-octanone and hexadecane promoted the growth of tobacco seedlings. The total VOCs from P. oligandrum also enhanced the shoot and root growth of ginger plants. Transcriptomic analysis showed a higher expression of genes related to plant growth hormones, and stress responses in the leaves of ginger plants exposed to P. oligandrum VOCs. The concentrations of plant growth hormones such as auxin, zeatin, and gibberellic acid were higher in the leaves of ginger plants exposed to P. oligandrum VOCs. In a ginger disease biocontrol assay, the VOC-exposed ginger plants infected with P. myriotylum had lower levels of disease severity. We conclude that this study contributes to understanding the growth-promoting mechanisms of P. oligandrum on ginger and tobacco, priming of ginger plants against various stress and the mechanisms of action of P. oligandrum as a biocontrol agent.
2023-06-22 | GSE235182 | GEO
Project description:Biofertilizers and pathogen biocontrol for sustainable maize cultivation
Project description:Nowadays one of the main challenges is moving towards an eco-sustainable agriculture, able to preserve the food production through a reduced use of pesticides. The current global food sustenance by intensive agriculture mainly based on economic crop monocultures drastically reduces the biodiversity increasing the yield losses due to biotic and abiotic stress. To try to ensure yield stability also enhancing the plant resistance responses to promote an eco-sustainable management of plant diseases, a technology based on plasma activated water (PAW), characterized by the production of reactive oxygen and nitrogen species, was tested. Differential expression levels of selected genes involved in the plant defence pathways and the microRNAs composition in PAW treated- micropropagated periwinkle shoots and grapevines were analyzed. The results indicate that PAW treatment enhances plant defence responses at both, transcriptional and post-transcriptional level, leading to an increased synthesis in periwinkle of vinblastine and vindoline, anti-oxidant compounds employed in the pharmaceutical industry and in grapevine of resveratrol that is an important compound for human health.
Project description:Regulatory science underpins the objective evaluation of medicinal products. It is therefore imperative that regulatory science and expertise remain at the cutting edge so that innovations of ever-increasing complexity are translated safely and swiftly into effective, high-quality therapies. We undertook a comprehensive examination of the evolution of science and technology impacting on medicinal product evaluation over the next 5-10 years and this horizon-scanning activity was complemented by extensive stakeholder interviews, resulting in a number of significant recommendations. Highlighted in particular was the need for expertise and regulatory science research to fill knowledge gaps in both more fundamental, longer-term research, with respect to technological and product-specific challenges. A model is proposed to realise these objectives in Europe, comprising a synergistic relationship between the European Medicines Agency, the European Medicines Regulatory Network and academic research centres to establish a novel regulatory science and innovation platform.
Project description:Food safety is an important scientific field, but at the same time a discussion topic of modern society that occupies more and more space of our every day time, dealing with the preparation of food, with its nutritious value, and various transportation and storage ways aiming at preventing food-related sickness. This work compares traditional farming with greenhouses and indoor vertical farming focusing on the challenges and the opportunities for each category. The scope of this work was to stress the role of indoor vertical farming towards this direction. Indoor vertical farms can produce high quality and virus-free products that can be locally distributed, inside the urban environment that such investments take place, saving annually millions of tons CO2 emissions. Beyond that, in this work it was pointed out how energy plays a role in food safety in such systems. It was stressed that indoor vertical farms can act as a demand response aggregator. In large scale units it could play a role to adjust their production according to different electricity prices offered in different time zones throughout the day. This way, the owners under a multi-value business model will create the opportunity to the vertical farm owners not only to improve their production but at the same time absorb inexpensive electricity offered, by creating an additional profit mechanism (multiple revenue streams) under such an approach by entering into contracts with companies in a utility electric region.
| S-EPMC7516583 | biostudies-literature
Project description:Whole Genome sequence of a Biocontrol agent for agriculture