Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Hepialus xiaojinensis isolate:RCRIBT_LabColony

ABSTRACT: Hepialus (Thitarodes) xiaojinensis isolate:RCRIBT_LabColony Genome sequencing

PROVIDER: PRJNA1006505 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR29185414_1.fastq.gz	Fastqsanger.gz
	SRR29185415_1.fastq.gz	Fastqsanger.gz
	SRR29185416_1.fastq.gz	Fastqsanger.gz
	SRR29185417_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 7

Similar Datasets

Hepialus xiaojinensis

Project description:Hepialus xiaojinensis overview

| PRJNA307130 | ENA

Hepialus xiaojinensis

Project description:Transcriptome of Thitarodes xiaojinensis

| PRJNA270787 | ENA

Hepialus xiaojinensis

Project description:Hepialus xiaojinensis Raw sequence reads

| PRJNA1104811 | ENA

Malus baccata var. xiaojinensis isolate:not collected | cultivar:Malus xiaojinensis

Project description:Malus baccata var. xiaojinensis isolate:not collected | cultivar:Malus xiaojinensis Genome sequencing

| PRJNA974501 | ENA

Project description:Thitarodes xiaojinensis

| PRJNA1264727 | ENA

Malus baccata var. xiaojinensis cultivar:Malus baccata var. xiaojinensis

Project description:Malus baccata var. xiaojinensis cultivar:Malus baccata var. xiaojinensis Transcriptome or Gene expression

| PRJNA392909 | ENA

Ophiocordyceps sinensis

Project description:Ophiocordyceps sinensis, Hepialus xiaojinensis, Hirsutella hepiali

| PRJNA376530 | ENA

Malus baccata var. xiaojinensis

Project description:Malus baccata var. xiaojinensis Transcriptome or Gene expression

| PRJNA215017 | ENA

Neurotransmitter acetylcholine mediates the mummification of Ophiocordyceps sinensis-infected Thitarodes xiaojinensis larvae (Metabolome data)

Project description:Parasites can manipulate host behavior to facilitate parasite transmission. One such host-pathogen interaction occurs between the fungus Ophiocordyceps sinensis (O. sinensis) and the ghost moth Thitarodes xiaojinensis. O. sinensis is involved in the mummification process of infected host larvae. However, the underlying molecular and chemical mechanism for this phenomenon is unknown. We characterized the small molecules regulating host behavior and the altered metabolites in infected and mummified host larvae. Lipid-related metabolites, such as phosphatidylcholine (PC) were identified in infected and mummified larvae. Decreased levels of the neurotransmitter acetylcholine (ACh) and elevated choline levels were observed in the brains of both the infected and mummified larvae. The aberrant activity of acetylcholinesterase (AChE) and relative mRNA expression of ACE2 (acetylcholinesterase) may mediate the altered transformation between ACh and choline, leading to the brain dysfunction of mummified larvae. Caspofungin treatment inhibited the mummification of infected larvae and the activity of AChE. These findings indicate the importance of ACh in the mummification of host larvae after O. sinensis infection. Metabolome data is reported in the current study <a href='https://www.ebi.ac.uk/metabolights/MTBLS9929' rel='noopener noreferrer' target='_blank'>MTBLS9929</a>.Lipidome data is reported in <a href='https://www.ebi.ac.uk/metabolights/MTBLS9930' rel='noopener noreferrer' target='_blank'>MTBLS9930</a>.

2024-08-05 | MTBLS9929 | MetaboLights

Neurotransmitter acetylcholine mediates the mummification of Ophiocordyceps sinensis-infected Thitarodes xiaojinensis larvae (Lipidome data)

Project description:Parasites can manipulate host behavior to facilitate parasite transmission. One such host-pathogen interaction occurs between the fungus Ophiocordyceps sinensis (O. sinensis) and the ghost moth Thitarodes xiaojinensis. O. sinensis is involved in the mummification process of infected host larvae. However, the underlying molecular and chemical mechanism for this phenomenon is unknown. We characterized the small molecules regulating host behavior and the altered metabolites in infected and mummified host larvae. Lipid-related metabolites, such as phosphatidylcholine (PC) were identified in infected and mummified larvae. Decreased levels of the neurotransmitter acetylcholine (ACh) and elevated choline levels were observed in the brains of both the infected and mummified larvae. The aberrant activity of acetylcholinesterase (AChE) and relative mRNA expression of ACE2 (acetylcholinesterase) may mediate the altered transformation between ACh and choline, leading to the brain dysfunction of mummified larvae. Caspofungin treatment inhibited the mummification of infected larvae and the activity of AChE. These findings indicate the importance of ACh in the mummification of host larvae after O. sinensis infection. Lipidome data is reported in the current study <a href='https://www.ebi.ac.uk/metabolights/MTBLS9930' rel='noopener noreferrer' target='_blank'>MTBLS9930</a>.Metabolome data is reported in <a href='https://www.ebi.ac.uk/metabolights/MTBLS9929' rel='noopener noreferrer' target='_blank'>MTBLS9929</a>.

2024-08-05 | MTBLS9930 | MetaboLights

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data