Project description:This study surveyed expression of genes which might be involved in regulating the satellite cell response to non-damaging exercise. Low density cDNA arrays were used to survey expression of selected cytokines and growth factors in the soleus muscle following 60 minutes of level running. Keywords: Exercise response; pre versus 24-hr post
Project description:To understand the role of LSD1 in transcriptional regulation in muscle under voluntary wheel running (VWR) training, RNA-seq analyses of soleus muscles of skeletal muscle-specific LSD1 KO mice (LSD1-mKO mice) and WT mice after VWR were carried out. We found that loss of LSD1 led to increased expression of oxidative metabolism genes in soleus muscle.