Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Resequencing data for Pu'an chicken

PROVIDER: PRJNA1022041 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR26205700_1.fastq.gz	Fastqsanger.gz
	SRR26205700_2.fastq.gz	Fastqsanger.gz
	SRR26205800_1.fastq.gz	Fastqsanger.gz
	SRR26205800_2.fastq.gz	Fastqsanger.gz
	SRR26205701_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 262

Similar Datasets

Mechanisms of hepatic steatosis in chickens: integrated analysis of the host genome, molecular phenomes and gut microbiome

Project description:Hepatic steatosis is the initial manifestation of abnormal liver functions and often leads to liver diseases such as non-alcoholic fatty liver disease in humans and fatty liver syndrome in animals. In this study, we conducted a comprehensive analysis of a large chicken population consisting of 705 adult hens by combining host genome resequencing, liver transcriptome, proteome, and metabolome analysis, as well as microbial 16S rRNA gene sequencing of each gut segment.

2024-04-09 | PXD042451 | Pride

Project description:Resequencing data for Luning Chicken

| PRJNA1025327 | ENA

Project description:Resequencing data for Yanying chicken

| PRJNA1018287 | ENA

Project description:Resequencing data for nami chicken

| PRJNA1015369 | ENA

Project description:JY chicken genome resequencing data

| PRJNA1099329 | ENA

Project description:Resequencing data for black-bone chicken

| PRJNA1021750 | ENA

Project description:Jinghong layer chicken genome resequencing data adapter

| PRJNA939426 | ENA

Gallus gallus

Project description:Resequencing data of Chinese domestic chicken (PRJCA034790)

| PRJDB34121 | ENA

Project description:Whole-genome resequencing data of Wuhua yellow chicken

| PRJNA1288062 | ENA

Mechanisms of hepatic steatosis in chickens: integrated analysis of the host genome, molecular phenomes and gut microbiome

Project description:<p>Hepatic steatosis is the initial manifestation of abnormal liver functions and often leads to liver diseases such as non-alcoholic fatty liver disease in humans and fatty liver syndrome in animals. In this study, we conducted a comprehensive analysis of a large chicken population consisting of 705 adult hens by combining host genome resequencing, liver transcriptome, proteome and metabolome analysis, as well as microbial 16S rRNA gene sequencing of each gut segment. The results showed the heritability (h2 = 0.25) and duodenal microbiability (m2 = 0.26) of hepatic steatosis were relatively high, indicating a large effect of host genetics and duodenal microbiota on chicken hepatic steatosis. Individuals with hepatic steatosis had low microbiota diversity and a decreased genetic potential to process triglyceride output from hepatocytes, fatty acid β-oxidation activity and resistance to fatty acid peroxidation. Furthermore, we revealed a molecular network linking host genomic variants (GGA6: 5.59-5.69 Mb), hepatic gene/protein expression (PEMT, phosphatidyl-ethanolamine N-methyltransferase), metabolite abundances (folate, S-adenosylmethionine, homocysteine, phosphatidyl-ethanolamine and phosphatidylcholine) and duodenal microbes (genus Lactobacillus) to hepatic steatosis, which could provide new insights into the regulatory mechanism of fatty liver development.</p>

2023-07-24 | MTBLS7808 | MetaboLights

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data