Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Genome-wide identification of transcriptional targets for GR in Caki-1 cells

ABSTRACT: Genome-wide identification of transcriptional targets for GR in Caki-1 cells

PROVIDER: PRJNA1029884 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR26434964_1.fastq.gz	Fastqsanger.gz
	SRR26434964_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 2 of 2

Similar Datasets

Genome-wide identification of transcriptional targets for GR in Caki-1 cells

Project description:To investigate the genome-wide transcription targets of GR in renal cell carcinoma, cleavage under targets and tagmentation (CUT&Tag) was performed in Caki-1 cells using antibodies againstGR. Following CUT&Tag, DNAs were amplified using non-biased conditions, labeled, and sequenced with Illumina NovaSeq 150PE.

2023-10-24 | GSE245752 | GEO

Identifying FOXA1-GR transcriptional targets in FOXA1-GR dependent NSCLC

Project description:Identifying FOXA1-GR transcriptional targets in FOXA1-GR dependent NSCLC

| PRJNA838217 | ENA

Genome-wide identification of transcriptional targets for H4K12 lactylation in ccRCC cells

Project description:To investigate the genome-wide transcription targets of H4K12 lactylation in ccRCC cells, cleavage under targets and tagmentation (CUT&Tag) was performed in 786-O and Caki-1 cells using antibody against H4K12 lactylation. Following CUT&Tag, DNAs were amplified using non-biased conditions, labeled, and sequenced with Illumina NovaSeq 150PE.

2026-01-23 | GSE315326 | GEO

Genome-wide identification of transcriptional targets of H4K12 lactylation and GR in 786-O cells with or without dexamethasone treatment.

Project description:To investigate the genome-wide transcriptional targets associated with H4K12 lactylation in renal cell carcinoma, cleavage under targets and tagmentation (CUT&Tag) was performed in 786-O cells with or without dexamethasone treatment using specific antibodies against H4K12 lactylation or GR. Following CUT&Tag, genomic DNA fragments were amplified under non-biased conditions and sequenced on the Illumina NovaSeq 150PE platform to generate high-resolution maps of H4K12 lactylation or GR–associated chromatin regions.

2026-01-23 | GSE315629 | GEO

Genome-wide identification of transcriptional targets for ING5

Project description:Genome-wide identification of transcriptional targets for ING5

| PRJNA672296 | ENA

Identifying FOXA1-GR transcriptional targets in FOXA1-GR dependent NSCLC

Project description:The FOXA1 pioneer factor is an essential mediator of steroid receptor function in multiple hormone dependent cancers, including breast and prostate cancers, enabling nuclear receptors such as ER and AR to activate lineage specific growth programs. . Analyzing data from loss-of-function screens, we identified a subset of NSCLC tumor lines where proliferation is FOXA1-dependent. Using rapid immunoprecipitation and mass spectrometry of endogenous protein (RIME) we identified chromatin-localized interaction between FOXA1 and glucocorticoid receptor (GR) in these tumor cells. Knockdown of GR inhibited proliferation of FOXA1-dependent, but not FOXA1-independent NSCLC cells. Here, we utilized ChIP-sequencing to identify a permissive set of genes potentially regulated by FOXA1 and GR to understand potential mechanisms underlying FOXA1-GR dependence in NSCLC.

2022-05-16 | GSE203036 | GEO

Identification of transcriptional targets of FGF20.

Project description:Identification of transcriptional targets of FGF20.

| PRJNA433812 | ENA

Genome-wide identification of transcriptional targets of H4K12 lactylation and GR in 786-O cells with or without dexamethasone treatment.

Project description:Genome-wide identification of transcriptional targets of H4K12 lactylation and GR in 786-O cells with or without dexamethasone treatment.

| PRJNA1398355 | ENA

Transcription profiling of Arabidopsis plants inducibly expressing LEC2:GR or ttg:GR to identify primary and secondary targets of the LEC2 transcription factor

Project description:Comparison of various inductibles constructions of arabidopsis treated by differents solutions. The aim of this project is to determine the primary and secondary targets of the LEC2 transcrition factor. The induction by the dexamethasone allows the expression of constructions LEC2:GR or ttg:GR introduced into transforming plants.The dexamethasone induces the expression of the contruct which carries the receptor to the glucocorticoïde (GR.). The cycloheximide is a inhibitor of the translation and allows, coupled with the dexamethasome, the identification of the primary targets only. The LEC2_GR25 and LEC2_GR31 constructs are two independents transforming plants of the cDNA-LEC2_GR construct. Both were used in order to have an idea of the variability of the data transcriptome obtained. The ttg_GR construct is used here as control ; ttg is another transcription factor, thus if induction with the dexamethasone works well, the targets induced in the two mutants will be different.

2007-01-01 | E-MEXP-807 | biostudies-arrayexpress

Genome-wide transcriptome analysis of VC and VHL-KO Caki-1 cells.

Project description:To compare the transcriptomic changes mediated by VHL knockout in Caki-1 cells, we carried out the next-generation sequencing (NGS)-derived transcriptomic profiling. We found significant enrichment of gene signatures involving IFNa/b signaling in VHL-KO Caki-1 cells compared to control cells. Our analysis also demonstrated that VHL deficiency induced the expression of genes associated with the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway involved in sensing the cytoplasmic presence of double-stranded DNA (dsDNA).

2024-08-10 | GSE196509 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data