Project description:We investigate the global miRNA expression profile of An. sinensis using illumine Hiseq 2000 sequencing.The annotation and prediction of miRNAs lays the foundation for the further functional study of An. sinensis miRNAs and will facilitate their application in vector control.
Project description:Chinese mitten crab (Eriocheir sinensis) is one of the most popular bred crustaceans in China. E. sinensis stressed by high temperature and resulted in disease and large mortality in summer. Litter is known about the mechanism of temperature tolerant E. sinensis. In this study, transcriptome and proteome for high temperature tolerant (HTT) and high temperature sensitive (HTS) female E. sinensis were identified
Project description:Clonorchiasis is associated with bile duct malignancy and the subsequent development of cholangiocarcinoma. Although this is likely caused by adult Clonorchis sinensis and its excretory-secretory products (ESP), the precise molecular mechanisms remain obscure. To evaluate the effect of C. sinensis infection on differential gene expression in host hepatocytes, we used cDNA microarrays in human cholangiocarcinoma cells through the mimicking of C. sinensis infestation, and analyzed differential mRNA expression patterns of host cells. Keywords: Time course