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Histone acetyl transferase HAF2 forms complex with PDC to regulate H3K14ac and H3K23ac in ethylene response

ABSTRACT: Histone acetyl transferase HAF2 forms complex with PDC to regulate H3K14ac and H3K23ac in ethylene response

PROVIDER: PRJNA1047065 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	SRR27000515_1.fastq.gz	Fastqsanger.gz
	SRR27000515_2.fastq.gz	Fastqsanger.gz
	SRR27000516_1.fastq.gz	Fastqsanger.gz
	SRR27000516_2.fastq.gz	Fastqsanger.gz

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Histone acetyl transferase HAF2 forms complex with PDC to regulate H3K14ac and H3K23ac in ethylene response [ChIP-seq]

Project description:Histone acetyl transferase HAF2 forms complex with PDC to regulate H3K14ac and H3K23ac in ethylene response [ChIP-seq]

| PRJNA1047072 | ENA

Histone acetyl transferase HAF2 forms complex with PDC to regulate H3K14ac and H3K23ac in ethylene response [RNA-seq]

Project description:Histone acetyl transferase HAF2 forms complex with PDC to regulate H3K14ac and H3K23ac in ethylene response [RNA-seq]

| PRJNA1047073 | ENA

Histone acetyl transferase HAF2 forms complex with PDC to regulate H3K14ac and H3K23ac in ethylene response

Project description:This SuperSeries is composed of the SubSeries listed below.

2025-06-16 | GSE249043 | GEO

Histone acetyl transferase HAF2 forms complex with PDC to regulate H3K14ac and H3K23ac in ethylene response [RNA-seq]

Project description:Next-generation sequencing (NGS) has been used to study the differential gene expression in Arabidopsis etiolated seedlings under air and ethylene treatment. The goal of this study is to investigate how HAF2 is involved in transcriptional regulation in response to ethylene.

2025-06-16 | GSE249042 | GEO

Histone acetyl transferase HAF2 forms complex with PDC to regulate H3K14ac and H3K23ac in ethylene response [ChIP-seq]

Project description:Next-generation sequencing (NGS) has been used to study the histone acetylation in Arabidopsis etiolated seedlings under air and ethylene treatment. The goal of this study is to investigate how HAF2 is involved in histone acetylation changes in response to ethylene.

2025-06-16 | GSE249041 | GEO

EIN2 mediates histone H3K14 and non-canonical histone H3K23 acetylation in the nucleus in ethylene response [ChIP-seq]

Project description:We report that ethylene specifically elevated acetylation of histone H3 at K14 and the non-canonical acetylation of histone H3 at K23. We perform Chip-sequencing of H3K14Ac, H3K23Ac and H3K9Ac using chromatins isolated from 3-day old etiolated Col-0 seedlings treated with ethylene or air gas. Results show that ethylene specifically elevates H3K14Ac and non-canonical H3K23Ac in EIN3 targeted genes that are regulated at the transcriptional level by ethylene.

2016-10-05 | GSE77394 | GEO

Epigenetic effects (H3K9ac, H3K14ac, H3K23ac and Pol II) of Kat6b loss in mouse neural stem cells (CUT&Tag)

Project description:Epigenetic effects (H3K9ac, H3K14ac, H3K23ac and Pol II) of Kat6b loss in mouse neural stem cells (CUT&Tag)

| PRJNA1112385 | ENA

Epigenetic effects (H3K9ac, H3K14ac, H3K23ac and Pol II) of Kat6b loss in mouse neural stem cells (CUT&Tag)

Project description:Heterozygous mutations in the histone acetyltransferase gene KAT6B (MYST4/MORF/QKF) cause cognitive disorders. Congruently, KAT6B is required for brain development, neural stem cell self-renewal and neuronal differentiation in mice. Despite the clear requirement for KAT6B in brain development, its molecular roles remain unexplored. Here we use CUT&Tag sequencing to determine the effects of loss or gain of KAT6B on H3K9ac and H3K23ac histone marks and on RNA Pol II.

2024-11-06 | GSE267672 | GEO

MOF acetyl transferase regulates transcription and respiration in mitochondria

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SPT6 Regulates H3K14Ac Deposition in Mouse Embryonic Stem Cells [PRO-seq]

Project description:SPT6 (suppressor of Ty 6) is a conserved histone chaperone that facilitates transcription elongation, nucleosome reassembly, and RNA polymerase II progression. The functions of SPT6 in regulating chromatin remain not fully understood. Here we show that SPT6 localized to H3K14Ac enriched regions and promoted H3K14Ac densities in mouse embryonic stem cells (mESCs). Loss of SPT6 results in decreased H3K14Ac and transcription. Mechanistically, we showed that SPT6 enhances the chromatin binding levels of acetyltransferases KAT7 and KAT6A/KAT6B. In addition, we showed that SPT6 also promotes H3K14Ac in a KAT7/6A/6B independent manner. Our findings identify a vital role of SPT6 in maintaining the integrity of H3K14Ac profile in mESCs, thus suggesting a crosstalk between transcription machinery and H3K14Ac in mammals.

2025-05-22 | GSE282181 | GEO

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