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Identification of microRNAs contained in extracellular vesicles derived from Pg-infected macrophages Description

ABSTRACT: Identification of microRNAs contained in extracellular vesicles derived from Pg-infected macrophages Description

PROVIDER: PRJNA1054083 | ENA |

REPOSITORIES: ENA

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Identification of microRNAs contained in extracellular vesicles derived from Pg-infected macrophages Description

Project description:Although miRNA analysis within Extracellular vesicles (EVs) has been explored in the context of various inflammatory diseases, limited research has been reported on EV-contained miRNAs associated with periodontal disease. Therefore, we comprehensively identified the specific miRNAs contained within EVs produced by macrophage-like cells infected with Pg.

2024-12-18 | GSE250449 | GEO

Project description:PG Raw sequence reads

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Cancer cells transfer invasive properties through microRNAs contained in collagen-tracks

Project description:Cancer cells transfer invasive properties through microRNAs contained in collagen-tracks

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Characterization of the small RNA content of Trypanosoma cruzi extracellular vesicles

Project description:A growing body of evidence in mammalian cells indicates that secreted vesicles can be used to mediate intercellular communication processes by transferring various bioactive molecules, including mRNAs and microRNAs. Based on these findings, we decided to analyze whether T. cruzi-derived extracellular vesicles contain RNA molecules and performed a deep sequencing and genome-wide analysis of a size-fractioned cDNA library (16M-bM-^@M-^S40 nt) from extracellular vesicles secreted by noninfective epimastigote and infective metacyclic trypomastigote forms. Our data show that the small RNAs contained in these extracellular vesicles originate from multiple sources, including tRNAs. In addition, our results reveal that the variety and expression of small RNAs are different between parasite stages, suggesting diverse functions. Taken together, these observations call attention to the potential regulatory functions that these RNAs might play once transferred between parasites and/or to mammalian host cells. Small RNAs profiles (16-40 nt) of epimastigote-derived extracellular vesicles, metacyclic trypomastigote-derived extracellular vesicles and metacyclic trypomastigote parental cells.

2014-07-15 | E-GEOD-54111 | biostudies-arrayexpress

Mycoplasmopsis canis PG 14 strain:PG 14

Project description:Mycoplasmopsis canis PG 14 strain:PG 14 Genome sequencing and assembly

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Mycoplasmopsis canis PG 14 strain:PG 14

Project description:Mycoplasmopsis canis PG 14 strain:PG 14 Genome sequencing and assembly

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MicroRNAs signatures from CSF extracellular vesicles of ParkinsonÃ¢Â€Â™s Disease patients

Project description:The diagnosis of ParkinsonÃ¢Â€Â™s disease (PD) lacks precision and occurs relatively late in disease progression. MicroRNAs are epigenetic regulators that have been used as biomarkers in various medical fields. Here, we used small RNA sequencing to quantify the microRNAome of extracellular vesicles isolated from human cerebrospinal fluid (CSF) of PD and control subjects (CTR) aiming to identify a microRNA-based signature for PD.

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Expression profile of microRNAs in serum extracellular vesicles isolated from 6 healthy subjects

Project description:Sera were collected from 6 healthy subjects, and the expression profiles of microRNAs in serum extracellular vesicles were investigated by 3D-gene microarray. The expression profile was used to investigate the correlation between immune responses to vaccines and microRNA expression levels.

2018-06-16 | GSE100128 | GEO

Sphingobacterium sp. PG-1

Project description:Sphingobacterium sp. PG-1 Assembly

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Effects of Moringa oleifera extracellular vesicles on human microRNAs involved in the HeLa cell tumorigenesis

Project description:The effects of extracellular vesicles from Moringa oleifera on the modulation of tumour associated human-microRNAs profile in cervical cancer-derived HeLa cells were investigated. Plant extracellular vesicles have been shown to carry a variety of bioactive compounds, such as proteins, lipids, phytochemicals (e.g., phenols and flavonoids), and RNAs, including nucleic acids (e.g., miRs), mediating the transfer of information to recipient cells and thus modulating their function and gene expression.

2025-10-02 | GSE309748 | GEO

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