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BMI1 regulates human erythroid self-renewal through both repressive and activating chromatin associations [Cut&Run]

ABSTRACT: BMI1 regulates human erythroid self-renewal through both repressive and activating chromatin associations [Cut&Run]

PROVIDER: PRJNA1064984 | ENA |

REPOSITORIES: ENA

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BMI1 regulates human erythroid self-renewal through both repressive and activating chromatin associations

Project description:BMI1 regulates human erythroid self-renewal through both repressive and activating chromatin associations

| PRJNA1064982 | ENA

BMI1 regulates human erythroid self-renewal through both repressive and activating chromatin associations [RNA-seq]

Project description:BMI1 regulates human erythroid self-renewal through both repressive and activating chromatin associations [RNA-seq]

| PRJNA1064985 | ENA

BMI1 regulates human erythroid self-renewal through both repressive and activating chromatin associations [Cut&Run]

Project description:To gain insights into the mechanisms underlying BMI1 activity we assessed binding of BMI1, the PRC1 member RING1B, and the PRC-associated histone marks H3K27me3 and H2AK119ub in SREs and in iSREs.

2025-07-28 | GSE253289 | GEO

BMI1 regulates human erythroid self-renewal through both repressive and activating chromatin associations [RNA-seq]

Project description:To assess transcriptional consequences of BMI1 overexpression, we performed RNA-seq in SREs and iSREs.

2025-07-28 | GSE253291 | GEO

BMI1 regulates human erythroid self-renewal through both repressive and activating chromatin associations

Project description:This SuperSeries is composed of the SubSeries listed below.

2025-07-28 | GSE253292 | GEO

Murine Myeloid-Erythroid Progenitors (MEPs): WT vs. Bmi1-/-

Project description:Transcriptional profiling of MEPs purified from wild type and Bmi1-/- mice. Two-condition experiment, WT vs. Bmi1-/- MEPs. Biological replicates: 3 WT replicates, 3 Bmi1-/- replicates.

2014-11-18 | E-GEOD-63411 | biostudies-arrayexpress

Murine Myeloid-Erythroid Progenitors (MEPs): WT vs. Bmi1-/-

Project description:Transcriptional profiling of MEPs purified from wild type and Bmi1-/- mice.

2014-11-18 | GSE63411 | GEO

Elucidation of BMI1, RYBP and H2AK119ub interactomes in Glioblastoma

Project description:Identification of BMI1, RYBP and H2AK119UB interactome in Glioblastoma (GBM) to elucidate BMI1 roles independent of the PRC1-complex in GBM.

2021-09-09 | PXD022057 | Pride

Transcriptome profiling of Bmi1 silenced-K562 CML cell line

Project description:The Bmi1 Polycomb protein is involved in the epigenetic repressive control of self renewal and survival of cancer initiating cells. In Chronic Myeloid Leukemia (CML), bmi1 expression increases gradually as the disease progresses from a chronic latent phase to a deadly blast crisis. We developped an inducible shRNA system to silence Bmi1 in the human K562 chronic myeloid leukemia (CML) cell line in order to identify new Bmi1-target genes.

2015-05-12 | GSE54262 | GEO

Transcriptome profiling of Bmi1 silenced-K562 CML cell line

2015-05-12 | E-GEOD-54262 | biostudies-arrayexpress