Project description:The purpose of this study is to determine whether cross feeding relationships can contribute to the alleviation of colitis. The two strains used in this study are Anaerostipes caccae and Bifidobacterium bifidum. Both strains are clearly present in significant amounts in the intestines of healthy humans. A. caccae is a butyrate-producing bacterium that uses lactic acid and acetate to produce butyrate. On the other hand, B. bifidum is known to produce lactic acid and acetate. The purpose of this study is to confirm the effect of the ecological network between the two strains on the improvement of colitis, particularly in terms of protecting intestinal epithelial cells.
Project description:Anaerostipes caccae strain L1-92T is a well-known butyrate-producing bacterium that has been isolated from human feces. In this announcement, we present the complete genome sequence of A. caccae strain L1-92T, which comprises 3,590,719 bp with a G+C content of 44.30%. The genome harbors 3,369 predicted protein-coding genes.
