ABSTRACT: Bacterial skin colonization with Propionibacterium avidum as a risk factor for Periprosthetic Joint Infections - a single-center prospective study
Project description:In 21 patients undergoing revision arthroplasty due to septic or aseptic implant loosening, synovial fluid was collected intraoperatively after opening the joint capsule. In a proteomic MS approach, we wanted now to investigate these synovial fluids for novel proteogenic markers of periprosthetic infections.
Project description:To explore the difference in the expression profile of Staphylococcus aureus in chronic periprosthetic joint infection (C_PJI) and acute PJI (A_PJI), we assayed S. aureus isolates from 4 C_PJI and 4 A_PJI by RNA-sequencing.
