Project description:4 cancer cell lines were treated with T-025 for 6 hours T-025 is a novel small molecule inhibitor of CLK. CLK is a kinase that regulates pre-mRNA splicing.
Project description:RNA-Seq analyses polysome-bound mRNAs of glioblastoma cell line NSC11 after 10nM (-)-SDS-1-021 treatement to evaluate drug-induced changes in mRNA translation