Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Effect of estrogen on transcriptomic profile in iWAT of old aged mice

ABSTRACT: Effect of estrogen on transcriptomic profile in iWAT of old aged mice

PROVIDER: PRJNA1087265 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR28329745_1.fastq.gz	Fastqsanger.gz
	SRR28329745_2.fastq.gz	Fastqsanger.gz
	SRR28329746_1.fastq.gz	Fastqsanger.gz
	SRR28329746_2.fastq.gz	Fastqsanger.gz
	SRR28329747_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Effect of estrogen on transcriptomic profile in iWAT of old aged mice

Project description:Beige adipocyes are compromised with aging even upon cold exposure. Besides, estrogen levels, which have metabolic benefit ,are also decreased with aging. However, the relationship between beige adipocyte and estrogen in aging remains poorly understood. In this study, the potential role of estrogen in iWAT of old aged mice was investigated. To elucidate functional outcomes, we performed RNA-sequencing analysis using vehicle treated group and estrogen treated group upon cold exposure

2024-03-18 | GSE261481 | GEO

Proteomics analysis of iWAT-EVs from young and aged mice

Project description:Proteomics analysis of iWAT-EVs to identify EV related markers in young and aged mice

2025-09-05 | PXD066710 | Pride

Effect of Lymph nodes removal on transcriptomic profile in iWAT of mice

Project description:There is a regional preference around lymph nodes (LNs) for adipose beiging upon cold exposure. However, the importance of this unique anatomical location remains poorly understood. In this study, the potential role of Lymph nodes in iWAT was investigated. to elucidate functional outcomes, we performed RNA-sequencing analysis using littermate sham and lymph nodes removal (LNR) mice upon cold exposure

2023-10-23 | GSE245718 | GEO

single cell RNA sequencing of hematopoietic stem cells aged in old and young niches

Project description:Purpose: Compare the transcriptome of hematopoietic stem cells (HSCs) that were aged in old and young niches Methods: barcoded GFP+ HSCs were FACS-sorted from a) three recipient mice 15 months post transplantation, and b) six serial transplantation recipient mice 5 months after the 8th transplantation, then subjected to processed using the Chromium Single-cell 3′ v2 Library Kit (10× Genomics, Pleasanton, CA) following the manufacturer’s instructions Results: we obtained transcriptomes of about 12k HSCs aged in young niche, and about 10k HSCs aged in old niche, with the average sequencing depth at close to 50k reads per cell Conclusions: we identified striking differences in gene expression profiles 1) between HSCs aged in young niches from mice with early aging and from mice with delayed aging, and 2) between HSCs aged in old niches and young niches when mice exhibited hematopoietic aging phenotype

2021-01-01 | GSE154772 | GEO

Comparison of expression profile between fibroblasts taken from young (23 years old) and aged (70 years old) donors

Project description:Comparison of expression profile between fibroblasts taken from young (23 years old) and aged (70 years old) donors

| PRJNA482433 | ENA

MicroRNA data in the hearts from young (8 week-old) and middle-aged (15 month-old) male mice

Project description:MicroRNAs have been reported to be involved in the regulation of cellular and organismal aging. However, little is known about the role of microRNAs in cardiac aging. We used microarrays to examine microRNA profiles in the hearts from young (8 week-old) and middle-aged (15 month-old) male mice.

2019-06-14 | GSE83329 | GEO

Hippocampal transcript profile in young and middle-aged mice

Project description:We carried out a global survey of age-related changes in mRNA levels in the C57BL/6NIA mouse hippocampus and found a difference in the hippocampal gene expression profile between 2-month-old young mice and 15-month-old middle-aged mice correlated with an age-related cognitive deficit in hippocampal-based explicit memory formation. Middle-aged mice displayed a mild but specific deficit in spatial memory in the Morris water maze. Keywords: age comparison

2006-06-20 | GSE5078 | GEO

Maternal PM2.5 Exposure Impairs Inguinal White Adipose Tissue Plasticity in Middle-aged Male Mouse Offspring

Project description:In this study, we investigated the long-term adverse metabolic effects of maternal fine particulate matter (PM2.5) exposure on offspring, systematically characterized the pathogenic remodeling of inguinal white adipose tissue (iWAT) in middle-aged male offspring through scRNA-seq, and explored the underlying mechanisms of iWAT fibrosis under in vivo and in vitro conditions.

2026-02-25 | GSE307673 | GEO

Mouse inguinal white adipose tissue (iWAT) LC-MS

Project description:Proteomic analysis of whole tissue and isolated mitochondria from iWAT in a mouse model of diet induced obesity with or without SANA.

2025-03-24 | PXD030485 | Pride

Trancriptomics effect of IL-17 blockade on aged murine epidermal cells [young vs old]

Project description:Trancriptomics effect of IL-17 blockade on aged murine epidermal cells [young vs old]

| PRJNA786221 | ENA