Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Early-onset breast cancer

PROVIDER: PRJNA1087680 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR28341700_1.fastq.gz	Fastqsanger.gz
	SRR28341700_2.fastq.gz	Fastqsanger.gz
	SRR28341703_1.fastq.gz	Fastqsanger.gz
	SRR28341703_2.fastq.gz	Fastqsanger.gz
	SRR28341706_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 192

Similar Datasets

Brca2

Project description:Mus musculus Brca2, breast cancer 2, early onset [Source:MGI Symbol;Acc:MGI:109337], is differentially expressed in 119 experiment(s);

| ENSMUSG00000041147 | ExpressionAtlas

Brca1

Project description:Mus musculus Brca1, breast cancer 1, early onset [Source:MGI Symbol;Acc:MGI:104537], is differentially expressed in 137 experiment(s);

| ENSMUSG00000017146 | ExpressionAtlas

Brca2

Project description:Mus musculus Brca2, breast cancer 2, early onset [Source:MGI Symbol;Acc:MGI:109337], is expressed in 35 baseline experiment(s);

| ENSMUSG00000041147 | ExpressionAtlas

Brca1

Project description:Mus musculus Brca1, breast cancer 1, early onset [Source:MGI Symbol;Acc:MGI:104537], is expressed in 35 baseline experiment(s);

| ENSMUSG00000017146 | ExpressionAtlas

Project description:Early-onset breast cancer sequencing

| PRJNA574486 | ENA

E-GEOD-16873

Project description:Early Dysregulation of Cell Adhesion and Extracellular Matrix Pathways in Breast Cancer Progression

2025-01-24 | E-GEOD-16873 | ExpressionAtlas

Breast Cancer Family Registry Early-onset Breast Cancer GWAS

Project description:Breast Cancer Family Registry Early-onset Breast Cancer GWAS

| PRJNA454751 | ENA

Breast Cancer Family Registry Early-onset Breast Cancer GWAS

Project description:Breast Cancer Family Registry Early-onset Breast Cancer GWAS

| PRJNA454752 | ENA

Expression data from breast cancer tissues and adjacent normal tissues

Project description:The early-onset breast cancer patients (age ≤40) often display higher incidence of axillary lymph node metastasis, and poorer five-year survival than the late-onset patients. To identify the genes and molecules associated with poor prognosis of early-onset breast cancer, we examined gene expression profiles from paired breast normal/ tumor tissues, and coupled with Gene Ontology and public data base analysis. Our data showed that the expression of GAS7b gene was lower in the early-onset breast cancer patients as compared to the elder patients. We found that GAS7 was associated with CYFIP1 and WAVE2 complex to suppress breast cancer metastasis via blocking CYFIP1 and Rac1 protein interaction, actin polymerization, and β1-integrin/FAK/Src signaling. We further demonstrated that p53 directly regulated GAS7 gene expression, which was inversely correlated with p53 mutations in breast cancer specimens. Our study uncover a novel regulatory mechanism of p53 in early-onset breast cancer progression through GAS7-CYFIP1 mediated signaling pathways.

2018-01-13 | GSE109169 | GEO

E-GEOD-7515

Project description:Transcription profiling by array of human breast cancer mammospheres and breast tumors

2025-01-24 | E-GEOD-7515 | ExpressionAtlas