Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Total RNA-seq from mice of NAc and mPFC

ABSTRACT: Total RNA-seq from mice of NAc and mPFC

PROVIDER: PRJNA1088184 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR28349591_1.fastq.gz	Fastqsanger.gz
	SRR28349591_2.fastq.gz	Fastqsanger.gz
	SRR28349592_1.fastq.gz	Fastqsanger.gz
	SRR28349592_2.fastq.gz	Fastqsanger.gz
	SRR28349593_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 16

Similar Datasets

Total RNA-seq from mice of NAc and mPFC

Project description:Total RNA-seq approach identified mRNAs and non-coding RNAs in the mouse NAc after Cocaine CPP conditioning and in the mPFC after social defeat stress.

2024-11-27 | GSE261663 | GEO

VTA and NAC labeled ribosome from mPFC

Project description:Projection-dependent ribosome profling from mouse mPFC. Ribosome from NAC- and VTA- projecting mPFC cells were immunoprecipited using GFP-trap (Chromotech). Translating mRNA was isolated and analyzed

2017-09-15 | GSE101185 | GEO

Transcriptome analysis of microglia isolated from the mPFC or NAc without or with repeated social defeat stress (R-SDS)

Project description:To identify R-SDS-induced changes in gene expression profiles in medial prefrontal cortex (mPFC) and nucleus accumbens (NAc) microglia, we performed transcriptome analysis in mPFC and NAc microglia without or with R-SDS. Based on our observation that TLR2/TLR4 mediate R-SDS-induced activation of mPFC microglia, we performed the analysis in wild-type (WT) mice and TLR2/TLR4-double knockout (TLR-DKO) mice.

2018-08-09 | GSE115995 | GEO

Effect of TSP1 on gene expression of mice mPFC

Project description:To investigate the role of TSP1 in the brain, we established the mPFC in mice after treatment with recombinant human thrombospondin-1 protein i.p.

2023-03-12 | GSE227035 | GEO

A genetically defined mPFC-thalamic circuit underlies pain chronicity

Project description:Chronic pain is a major health care problem with great social and economic consequences. Although the medial prefrontal cortex (mPFC) and the thalamus have been implicated in regulating pain, whether and how these regions may involve in pain chronification process have remained largely unknown. Here, we show that Foxp2+ neurons in mPFC, which are corticothalamic (CT) neurons representing the major mPFC output to thalamus, are deactivated in chronic inflammatory pain. Interestingly, prolonged, but not short-term, inactivation of the Foxp2+ neurons in mPFC increases the sensitivity to noxious stimulations. Conversely, chemogenetic activation of this neuronal cluster induces robust antinociceptive effects in both naïve mice and mice with chronic inflammatory pain. Furthermore, we found that the mPFC Foxp2+ neurons project to several thalamic relay nuclei and that activation of the mPFC to the parataenial nucleus of thalamus (PTN) circuit relieves pain. Finally, RNA-seq of the mPFC Foxp2+ neurons revealed that many genes related to neuronal activity are dysregulated in mice with chronic inflammatory pain. Collectively, our studies revealed that Foxp2+ neurons in mPFC that project to thalamus play a critical role in somatosensory processing and pain chronification.

2023-09-16 | GSE243136 | GEO

Effect of TSP1 on peotein expression of mice mPFC

Project description:To investigate the role of TSP1 in the brain, we established the mPFC in mice after treatment with recombinant human thrombospondin-1 protein i.p.

2023-03-07 | PXD040646 |

Effect of TSP1 on gene expression of mice mPFC

Project description:Effect of TSP1 on gene expression of mice mPFC

| PRJNA942936 | ENA

Medial prefrontal cortex (mPFC) transcriptome analysis of Shank3-overexpressing mice

Project description:Shank3 is a core excitatory postsynaptic protein expressed in multiple brain regions including the medial prefrontal cortex, striatum, and hippocampus. We have previously generated and characterized Shank3-overexpressing transgenic mice, and found that these mice exhibited manic-like behavioral phenotypes. To understand molecular mechanisms underlying the behavioral changes, we performed transcriptome (RNA-sequencing) analysis of the mPFC tissues from 10 to 12-week-old wild-type and Shank3 transgenic mice.

2018-12-25 | GSE113368 | GEO

RNA-Seq in WT and Cav3.1 knock-out mPFC with or without chronic stress

Project description:The balk RNA-seq in WT and Cav3.1 knock-out (KO) mPFC with or without chronic stress was done to detect gene transcripcts assiciated with chronic stress-induced depressive-like bahaviors in mice.

2025-07-01 | GSE283828 | GEO

RNA-Seq in WT and Cav3.1 knock-out female mPFC with or without chronic stress

Project description:The bulk RNA-seq in WT and Cav3.1 knock-out (KO) female mPFC with or without chronic stress was done to detect gene transcripcts assiciated with chronic stress-induced depressive-like bahaviors in mice.

2025-07-01 | GSE292290 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data