Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Effect of oral administration of Si-based agent on renal mRNA expression.

ABSTRACT: Effect of oral administration of Si-based agent on renal mRNA expression.

PROVIDER: PRJNA1088189 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR28349523.fastq.gz	Fastqsanger.gz
	SRR28349524.fastq.gz	Fastqsanger.gz
	SRR28349525.fastq.gz	Fastqsanger.gz
	SRR28349526.fastq.gz	Fastqsanger.gz
	SRR28349527.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 15

Similar Datasets

Effect of oral administration of Si-based agent on renal mRNA expression.

Project description:Oral administration of Si-based agents produces large amounts of hydrogen under alkaline conditions in the intestinal tract. Hydrogen removes reactive oxygen species and reduces oxidative stress. It is also known that oxidative stress is involved in the progression of renal fibrosis. We reported that oral administration of Si- based agent suppressed renal fibrosis using UUO model. mRNA expression in Sham group, UUO group, and UUO+Si group was evaluated by RNA-seq and functional analysis, and found that fibrosis-related Gene ontology and Pathways related to fibrosis were suppressed by the Si-based agent.

2025-03-02 | GSE261665 | GEO

An open-label, phase II basket study of an oral hypomethylating agent CC-486 and durvalumab in advanced solid tumors

Project description:Purpose: To evaluate whether administration of the oral DNA hypomethylating agent (HMA) CC-486 enhances the poor response rate of immunologically ‘cold’ solid tumors to immune checkpoint inhibitor durvalumab.

2020-07-26 | GSE147537 | GEO

Expression from L4/5 DRGs after oral administration of LBP

Project description:Current study found that oral administration markedly increased the growth capacity of DRG neurons. In this dataset, we identified genes that were differentially expressed in L4/5 DRGs after oral administration of LBP

2022-10-01 | GSE200112 | GEO

Oral administration of engineered yeast produced H5HA-based vaccines

Project description:Oral administration of engineered yeast produced H5HA-based vaccines

| PRJNA911230 | ENA

Subacute toxicity study of nicotinamide mononucleotide via oral administration

Project description:Subacute toxicity study of nicotinamide mononucleotide via oral administration

| PRJNA662085 | ENA

RNA-seq of circulating human eosinophils before and after oral prednisone administration

Project description:Glucocorticoids are first-line agents for the treatment of many eosinophil-associated disorders. However, their mechanism of action in this group of disorders remains poorly understood, including the well-known clinical observation that glucocorticoids at therapeutic doses lead to profound, transient eosinopenia within hours of administration. To gain an unbiased, genome-wide view of the early transcriptional effects of glucocorticoids on human eosinophils in vivo, and torelate them to the kinetics of glucocorticoid-induced eosinopenia, RNA sequencing was performed on purified blood eosinophils obtained before and 30, 60, and 120 minutes after administration of a single dose of oral prednisone (1 mg/kg) to healthy subjects with hypereosinophilia (hypereosinophilia of unknown significance).

2018-07-19 | GSE111789 | GEO

Next Generation Sequencing of si-NC and si-circFAM120A Transcriptomes

Project description:Purpose: to find the potential down-stream target gene of circFAM120A Methods: mRNA profiles of decidualized human endometrial stromal cells (hESCs) after down-regulated FAM120A and control using siRNA were generated by NGS and compared by bioinformatics analysis Results: we sequenced 26414 mRNAs in hESCs between the si-NC and si-circFAM120A groups and identified 242 differentially expressed mRNAs, between which 161 were downregulated and 81 were up-regulated in si-circFAM120A group Conclusions: Our study represents the detailed analysis of decidualized hESCs transcriptomes between si-NC and si-circFAM120A groups.

2023-06-30 | GSE174495 | GEO

Chronic oral administration of nicotine affects transcriptomic profiling in conditional Presenilin 1/2 knockout mice and wild type mice

Project description:we found that chronic oral (3 months) administration of nicotine had different effects on transcriptomic profiling in prefrontal forebrain cortex of wildtype (WT) and Presenilin 1/2 double knockout mice.

2024-01-01 | GSE211983 | GEO

Implement enhanced artificial “intestinal enteroendocrine L cells” via oral administration for effective treatment of type 2 diabetes

Project description:Intestinal enteroendocrine L cells, responsive for secreting glucagon-like peptide-1 (GLP-1) to normalize blood glucose level, are negatively affected when type 2 diabetes (T2D) develops. Here, we designed enhanced artificial “intestinal enteroendocrine L cells” (EcN-GLP-1@Fe-TA-Pe@CLGN) for T2D treatment via oral administration.

2024-08-09 | PXD054739 |

Expression from L4/5 DRGs after oral administration of LBP

Project description:Expression from L4/5 DRGs after oral administration of LBP

| PRJNA823011 | ENA