Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Chromatin and gene expression profile at single nuclei level of CD45+ leukocytes from the rhesus brain parenchyma

ABSTRACT: Chromatin and gene expression profile at single nuclei level of CD45+ leukocytes from the rhesus brain parenchyma

PROVIDER: PRJNA1089650 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR28390551.fastq.gz	Fastqsanger.gz
	SRR28390552.fastq.gz	Fastqsanger.gz
	SRR28390554.fastq.gz	Fastqsanger.gz
	SRR28390554_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 15

Similar Datasets

Chromatin and gene expression profile at single nuclei level of CD45+ leukocytes from the rhesus brain parenchyma

Project description:We used Chromium Single Cell Multiome ATAC + Gene Expression to analyze CD45+ leukocytes in the rhesus macaque brain during homeostasis and chronic SIV infection

2024-03-26 | GSE261968 | GEO

Rhesus macaque cecal CD45+ leukocytes

Project description:Rhesus macaque cecal CD45+ leukocytes

| PRJEB73798 | ENA

Rhesus macaque cecal CD45+ leukocytes

Project description:10X transcriptomics + B cell V(D)J sequencing of CD45+ leukocytes

2024-04-30 | E-MTAB-13902 | biostudies-arrayexpress

Transcriptional analysis of CD45+ leukocytes isolated from syngeneic MC38 tumors from mice fed high-fat or control diet

Project description:Examination of transcriptional changes associated with diet-induced obesity in tumor-infiltrating CD45+ leukocytes from syngeneic MC38 colorectal tumors.

2020-12-15 | GSE157990 | GEO

Single-nuclei sequencing of late gestation rhesus macaques exposed to chorioamnionitis

Project description:We used single-nuclei sequencign to determine the effect of chorioamnionitis to the developing cerebellum using a rhesus macaque model of chorioamnionitis induced by intra-amniotic LPS.

2024-01-17 | GSE205001 | GEO

CD45+ vs CD45- RCC proteome characterization

Project description:Exploration of proteome differences between CD45+ and CD45- cell types in renal cell carcinoma tumors and normal adjacent tissue patient samples.

2020-10-14 | PXD014370 | Pride

Leukocytes

Project description:Leukocytes

| PRJNA576499 | ENA

Single-nuclei sequencing of late gestation rhesus macaques exposed to chorioamnionitis

Project description:Single-nuclei sequencing of late gestation rhesus macaques exposed to chorioamnionitis

| PRJNA843047 | ENA

Stroke induces disease-specific myeloid cells in the brain parenchyma and pia

Project description:Inflammation triggers secondary brain damage after stroke. The meninges and other CNS border compartments serve as invasion sites for leukocyte influx into the brain thus promoting tissue damage after stroke. However, the post-ischemic immune response of border compartments compared to brain parenchyma remains poorly characterized . Here, we deeply characterize tissue-resident leukocytes in meninges and brain parenchyma by flow cytometry, histology, and single cell transcriptomics after experimental stroke and discover that leukocytes respond differently to stroke depending on their site of residence. We thereby discover a unique phenotype of myeloid cells exclusive to the brain after stroke. These stroke-associated myeloid cells partially resemble neurodegenerative disease-associated microglia. They are mainly of resident microglial origin, partially conserved in humans and exhibit a lipid-phagocytosing phenotype. Blocking markers specific for these cells partially ameliorates stroke outcome thus providing a potential therapeutic target. The injury-response of myeloid cells in the CNS is thus compartmentalized, adjusted to the type of injury and may represent a therapeutic target.

2021-11-26 | GSE189432 | GEO

Illumina microarray analysis of three subpopulations of murine aortic adventitial cells freshly sorted by MACS, based on expression of Sca-1 and CD45

Project description:Comparison of gene expression between aortic adventitial Sca-1+CD45+ progenitor cells and Sca-1-CD45+ or Sca-1+CD45- cells. The hypothesis tested was that Sca-1+CD45+ cells would differentially express genes relating to angiogenesis and vasculogenesis when compared to Sca-1-CD45+ leukocytes.

2019-03-06 | GSE127852 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data