Project description:Even if a large amount of high-throughput functional genomic data exists, most researchers feature a strong background in molecular biology but lack advanced bioinformatics skills. In this work, publicly available gene expression datasets have been analyzed giving rise to a total of 40,224 gene expression profiles within different Cannabis tissues/developmental stages. The resource here proposed will provide researchers with a starting point for future investigations of Cannabis sativa.
Project description:Low temperature is a major abiotic stress factor that promotes oxidative stress and disrupts cellular homeostasis, ultimately impairing plant physiological functions. This study investigated the effects of exogenous putrescine treatment on the cold stress response of Cannabis sativa L. This in silico transcriptome analysis demonstrated that putrescine mediates cold stress tolerance in C. sativa, providing valuable insight for future in vitro validation studies and a foundational framework for the development of cold-resistant hemp cultivars.
Project description:Low temperature is a major abiotic stress factor that promotes oxidative stress and disrupts cellular homeostasis, ultimately impairing plant physiological functions. This study investigated the effects of exogenous putrescine treatment on the cold stress response of Cannabis sativa L. This in silico transcriptome analysis demonstrated that putrescine mediates cold stress tolerance in C. sativa, providing valuable insight for future in vitro validation studies and a foundational framework for the development of cold-resistant hemp cultivars.
Project description:This clinical trial studies the effectiveness of a web-based cancer education tool called Helping Oncology Patients Explore Genomics (HOPE-Genomics) in improving patient knowledge of personal genomic testing results and cancer and genomics in general. HOPE-Genomics is a web-based education tool that teaches cancer/leukemia patients, and patients who may be at high-risk for developing cancer, about genomic testing and provide patients with information about their own genomic test results. The HOPE-Genomics tool may improve patient’s genomic knowledge and quality of patient-centered care. In addition, it may also improve education and care quality for future patients.
Project description:Cannabis sativa, a member of the Cannabaceae family, is predominantly a dioecious species, producing male and female flowers on separate individuals. Although sex determination follows a heterogametic XY system, considerable plasticity in sex expression is evident. To investigate the gene regulatory networks underlying male and female flower development, we performed transcriptomic profiling of shoot apices from vegetative male and female inflorescences at one and three weeks following floral induction. Our analysis identified key MADS-box genes associated with floral organ specification and revealed that cannabis flower development largely conforms to the canonical ABCDE model
Project description:Cannabis sativa L., which has been reclassified as an agronomic crop, has experienced an increase in cultivation. Its interactions with a variety of environmental stressors have been extensively studied. However, the mechanisms of recovery through fungal associations remain underexplored. Trichoderma hamatum, known for its role as a biological agent, enhances plant growth and provides antagonistic defense against pathogenic microbes. This meta-dataset aims to investigate whether Th can enhance drought resistance in a Cannabis plants.