Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNAseq analysis of sex differences of young and old hematopoietic stem cells

ABSTRACT: RNAseq analysis of sex differences of young and old hematopoietic stem cells

PROVIDER: PRJNA1090527 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR28412874.fastq.gz	Fastqsanger.gz
	SRR28412875.fastq.gz	Fastqsanger.gz
	SRR28412876.fastq.gz	Fastqsanger.gz
	SRR28412877.fastq.gz	Fastqsanger.gz

Items per page:

1 - 4 of 4

Similar Datasets

Single cell transcriptomics of sex differences of young and old hematopoietic stem cells

Project description:Single cell transcriptomics of sex differences of young and old hematopoietic stem cells

| PRJNA1090472 | ENA

RNAseq analysis of sex differences of young and old hematopoietic stem cells

Project description:Bulk RNA sequencing (RNAseq) analysis of hematopoietic stem/progenitor cells purifiied from young and longevity mice, both male and female.

2024-10-29 | GSE262180 | GEO

Single cell transcriptomics of sex differences of young and old hematopoietic stem cells

Project description:Single cell RNA sequencing (scRNAseq) analysis of hematopoietic stem/progenitor cells purifiied from young and longevity mice, both male and female.

2024-10-29 | GSE262145 | GEO

Young and Old Mouse Parabiosis Hematopoietic Stem Cell RNA Sequencing

Project description:RNA sequencing of hematopoietic stem cells isolated from young (8-12 week) and old (24-27 month) BL6 mice from experimental groups that are intended to describe the transcriptomic consequences of parabiosis on the function of old hematopoietic stem cells.

2021-05-17 | GSE134417 | GEO

single cell RNA sequencing of hematopoietic stem cells aged in old and young niches

Project description:Purpose: Compare the transcriptome of hematopoietic stem cells (HSCs) that were aged in old and young niches Methods: barcoded GFP+ HSCs were FACS-sorted from a) three recipient mice 15 months post transplantation, and b) six serial transplantation recipient mice 5 months after the 8th transplantation, then subjected to processed using the Chromium Single-cell 3′ v2 Library Kit (10× Genomics, Pleasanton, CA) following the manufacturer’s instructions Results: we obtained transcriptomes of about 12k HSCs aged in young niche, and about 10k HSCs aged in old niche, with the average sequencing depth at close to 50k reads per cell Conclusions: we identified striking differences in gene expression profiles 1) between HSCs aged in young niches from mice with early aging and from mice with delayed aging, and 2) between HSCs aged in old niches and young niches when mice exhibited hematopoietic aging phenotype

2021-01-01 | GSE154772 | GEO

Myelin proteome differences in old and young mice

Project description:Aging of the peripheral nervous system (PNS) is associated with structural and functional changes that lead to a reduction in regenerative capacity and the development of age-related peripheral neuropathy. Myelin is a central component in maintaining physiological peripheral nerve function, and differences in myelin maintenance, degradation, formation and clearance have been suggested to contribute to age-related PNS changes. In addition, recent proteomic studies have elucidated the complex composition of the total myelin proteome in health and its changes in neuropathy models. However, changes in the myelin proteome of peripheral nerves during ageing have not been investigated. Hence, the aim of this proteomics experiment was to define proteome changes in isolated myelin fractions during ageing, by investigating myelin proteome profiles from young (nerves from 2-3 month old mice) and old (nerves from 18 months old mice) nerves.

2023-10-19 | PXD040719 | Pride

Young and Old Mouse Parabiosis Hematopoietic Stem Cell RNA Sequencing

Project description:Young and Old Mouse Parabiosis Hematopoietic Stem Cell RNA Sequencing

| PRJNA555158 | ENA

Young and Old Mouse Parabiosis Hematopoietic Stem Cell RNA Sequencing

Project description:Young and Old Mouse Parabiosis Hematopoietic Stem Cell RNA Sequencing

| PRJNA555106 | ENA

Transcriptomic analysis of sex differences in hematopoietic stem cell aging

Project description:Transcriptomic analysis of sex differences in hematopoietic stem cell aging

| PRJNA1090524 | ENA

RNA-seq reveals differences in liver gene expression rhythms between young and old mice

Project description:Purpose: We used RNA-seq to compare daily rhythms of gene expression in livers of young and old mice. Methods: Livers of young and old mice were processed for RNA-seq at 4-h interval across 2 days. Gene expression level was analyzed by hisat2 and StringTie. Results: We obtained ~10 million high quality sequencing reads per time point per sample after quality control and alignment. Gene expression levels of ~19,000 transcripts were obtained for both age groups. We found genome-wide differenes in gene expression level as well as rhythms in gene expression. Conclusions: Our study revealed genomwide differences in the level and rhythm of liver gene expression between young and old mice.

2019-12-31 | GSE113745 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data