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Overexpression of miR-200c/141 and miR-200b/200a/429 in MDA-MB-436 cells

ABSTRACT: Overexpression of miR-200c/141 and miR-200b/200a/429 in MDA-MB-436 cells

PROVIDER: PRJNA1091958 | ENA |

REPOSITORIES: ENA

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Overexpression of miR-200c/141 and miR-200b/200a/429 in MDA-MB-436 cells

Project description:We previously showed that overexpression of the miR-200c/141 cluster in the TNBC cell line MDA-MB-231 significantly reduced proliferation and invasion in vitro and tumor growth and metastasis in vivo. To confirm the effects of miR-200s in another TNBC cell line, MDA-MB-436 cells were created to overexpress both the miR-200c/141 cluster and the miR-200b/200a/429 cluster.

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Transgenic overexpression of the miR-200b/200a/429 cluster prevents mammary tumor development in MTB-TAN mice

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Searching for target genes of miR-429 in HCCLM3 cells

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Project description:miR-200b/200a/429 cluster prevents metastasis and induces dormancy in murine claudin-low mammary tumor cells

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Transgenic overexpression of the miR-200b/200a/429 cluster prevents mammary tumor development in MTB-TAN mice

Project description:Transgenic overexpression of the miR-200b/200a/429 cluster prevents mammary tumor development in MTB-TAN mice

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