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Effect of knockout of Samsn1 on gene expression during E.coli infection in Raw264.7 cells

ABSTRACT: Effect of knockout of Samsn1 on gene expression during E.coli infection in Raw264.7 cells

PROVIDER: PRJNA1092993 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	SRR28490635_1.fastq.gz	Fastqsanger.gz
	SRR28490635_2.fastq.gz	Fastqsanger.gz
	SRR28490637_1.fastq.gz	Fastqsanger.gz
	SRR28490637_2.fastq.gz	Fastqsanger.gz

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Effect of knockout of Samsn1 on gene expression during E.coli infection in Raw264.7 cells

Project description:In sepsis, infection and immunosuppression occur simultaneously. We currently found that Samsn1 expression is increased on myeloid cells in sepsis. And, Samsn1 is currently recognized as a negative regulator of immune response. So we constructed Samsn1 knockout Raw264.7 cells to study the effect of Samsn1 on macrophage function and the gene expression of macrophages with infection.

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Characterization of the chemokine response of RAW264.7 cells to infection by murine norovirus

Project description:RAW264.7 macrophages infected with MNV-1 and mock infected gene expression measured by microarray. To be published in Waugh, E. Chen, A. Baird, M. Fleming, S. Brown, C.M. and V K. Ward (2014) Characterization of the chemokine response of RAW264.7 cells to infection by murine norovirus. Virus Genes Four Samples, two mock and two MNV-1 infected.

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