Project description:FTLD-U is the most common pathological correlate of the neurodegenerative dementia frontotemporal dementia; We used microarrays to perform global expression profiling of FTLD-U brain samples Experiment Overall Design: Postmortem brain samples were isolated from normal controls, FTLD-U patients with progranulin gene mutations (progranulin) and FTLD-U patients without progranulin gene mutations (sporadic). Regional dissections were carried out from frontal cortex, hippocampus, and cerebellum.
Project description:Protein expression in the temporal cortex brain samples of normal, Alzheimer's and Progressive supranuclear palsy samples from the Mayo Clinic Brain Bank
