Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: pH buffering activity of the oral probiotic strain Streptococcus dentisani through arginine and agmatine metabolism

PROVIDER: PRJNA1103411 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR28778067.fastq.gz	Fastqsanger.gz

Items per page:

1 - 1 of 1

Similar Datasets

Streptococcus dentisani 7746 complete genome.

Project description:Genomic and experimental analysis of S. dentisani 7746 demonstrates pH buffering capacity.

| PRJEB68375 | ENA

Arginine-dependent gene regulation in Streptococcus gordonii arcR regulator knockout

Project description:We have previously shown that responses of the oral bacterium Streptococcus gordonii to arginine are co-ordinated by three paralogous regulators: ArcR, ArgR and AhrC. This set of experiments was designed to assess the effects of the ArcR gene regulator on global gene expression in Streptococcus gordonii under high arginine or following a shift to no arginine.

2017-07-18 | GSE101505 | GEO

Arginine-dependent gene regulation in Streptococcus gordonii ahrC regulator knockout

Project description:We have previously shown that responses of the oral bacterium Streptococcus gordonii to arginine are co-ordinated by three paralogous regulators: ArcR, ArgR and AhrC. This set of experiments was designed to assess the effects of the AhrC gene regulator on global gene expression in Streptococcus gordonii under high arginine or following a shift to no arginine.

2017-07-18 | GSE101507 | GEO

Arginine-dependent gene regulation in Streptococcus gordonii ArgR regulator knockout

Project description:We have previously shown that responses of the oral bacterium Streptococcus gordonii to arginine are co-ordinated by three paralogous regulators: ArgR, ArgR and AhrC. This set of experiments was designed to assess the effects of the ArgR gene regulator on global gene expression in Streptococcus gordonii under high arginine or following a shift to no arginine.

2017-07-18 | GSE101506 | GEO

Arginine-specific effects on the transcriptome of Streptococcus mutans probed by RNA-seq

Project description:Streptococcus mutans is a common constituent of oral biofilms and a primary etiologic agent of human dental caries. The bacteria associated with dental caries have a potent ability to produce organic acids from dietary carbohydrates and to grow and metabolize in acidic conditions. In this study, we observed supplementation with 1.5% arginine (final concentration) had inhibitory effects on the growth of S. mutans in complex and chemically defined media, particularly when cells were exposed to acid or oxidative stress. Deep-sequencing of RNA (RNA-Seq) comparing the transcriptomes of S. mutans growing in a chemically defined medium with and without 1.5% arginine in neutral and acidic pH conditions and under oxidative stress conditions revealed interesting results. The results provide new insights into the mechanisms of action by which arginine inhibits dental caries through direct adverse effects on multiple virulence-related properties of the most common human dental caries pathogen. The findings significantly enhance our understanding of the genetics and physiology of this cariogenic pathogen.

2017-05-20 | GSE98020 | GEO

ArgR1 and AhrC Mediate Arginine-Dependent Regulation of Arginine Acquisition- and Virulence Genes in the Human Pathogen Streptococcus pneumoniae

Project description:This SuperSeries is composed of the following subset Series: GSE33033: ahrC mutant compared to D39 wild-type in Streptococcus pneumoniae in CDM + 10 mM arginine GSE33034: argR1 mutant compared to D39 wild-type in Streptococcus pneumoniae in CDM + 10 mM arginine GSE33035: argR1-ahrC mutant compared to D39 wild-type in Streptococcus pneumoniae in CDM + 10 mM arginine GSE33036: Streptococcus pneumoniae D39 wild-type grown in CDM+10 mM arginine compared to D39 wild type grown in CDM + 0.05 mM arginine Refer to individual Series

2011-11-02 | E-GEOD-33043 | biostudies-arrayexpress

Growth phase-associated changes in Lactobacillus rhamnosus GG

Project description:Transcriptional profiling of probiotic Lactobacillus rhamnosus GG during growth in industrial-type whey medium in pH-controlled bioreactor cultures at two different growth pH: 4.8 and 5.8. Keywords: growth phase, growth pH

2011-08-01 | GSE28903 | GEO

Streptococcus pneumoniae D39 wild-type grown in CDM+10 mM arginine compared to D39 wild type grown in CDM + 0.05 mM arginine

Project description:Comparison of Streptococcus pneumoniae D39 wild-type grown in CDM+10 mM arginine compared to D39 wild type grown in CDM + 0.05 mM arginine to define the genome-wide transcriptional response to arginine. Details described in Kloosterman TG and Kuipers OP. ArgR1 and AhrC Mediate Arginine-Dependent Regulation of Arginine Acquisition- and Virulence Genes in the Human Pathogen Streptococcus pneumoniae. JBC 2011 Two condition design comparison of wild type strain

2011-11-02 | E-GEOD-33036 | biostudies-arrayexpress

Metabolic network construction reveals probiotic-specific colonization resistance in a synthetic small intestinal community

Project description:<p>The gut microbiota is essential to host health. Probiotics can be used as a microbiota targeted therapy to improve host health. However, probiotic molecular mechanisms of action and probiotics targeting the small intestinal microbiota are often not elucidated. In this study, we construct a three species synthetic community resembling the upper small intestine. We show that probiotic supplementation results in direct colonization resistance by affecting the metabolism of the community in a probiotic specific manner. Supplementation with Streptococcus thermophilus increased lactate production and reduced the pH, but did not affect the overall metabolic network substantially. In contrast, Lactobacillus casei did not alter lactate production or the pH, but increased the resistance to perturbations and nutrient utilization. Furthermore, supplementation of L. casei together with kynurenine increased metabolism along the kynurenine pathway and resulted in an elevated concentration of kynurenic acid, possibly leading to indirect colonization resistance. Together, we show how network construction can be used to improve the current or identify novel microbiota-targeted therapies.</p>

2024-09-26 | MTBLS7370 | MetaboLights

Streptococcus salivarius

Project description:genome of oral probiotic Streptococcus salivarius 24SMBc

| PRJNA865118 | ENA