Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Bulk RNA sequencing of livers from high fat diet plus carbon tetrachloride challenged Chrna2 fl/fl and Chrna2 fl/fl AlbCre mice.

ABSTRACT: Bulk RNA sequencing of livers from high fat diet plus carbon tetrachloride challenged Chrna2 fl/fl and Chrna2 fl/fl AlbCre mice.

PROVIDER: PRJNA1103807 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR28784481_1.fastq.gz	Fastqsanger.gz
	SRR28784481_2.fastq.gz	Fastqsanger.gz
	SRR28784482_1.fastq.gz	Fastqsanger.gz
	SRR28784482_2.fastq.gz	Fastqsanger.gz
	SRR28784483_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Naïve and LCMV Cl13 infected liver tissue of ERT2 AlbCre Ifnar1 fl/fl mice

Project description:Age- and sex-matched (male, 2-3 months old) ERT2 AlbCre Ifnar fl/fl and ERT2 AlbCre Ifnar +/+ mice were injected intraperitoneally with 40 mg/kg tamoxifen for 5 consective days. Mice were then intravenously infected with 2x10^6 focus forming units of LCMV Cl13 and liver tissue of either genotype was harvested 1.5 days post infection and analyzed for transcriptomic changes (n = 3). Liver tissue of uninfected animals of both genotypes was harvested as control (n = 3).

2019-12-05 | GSE117237 | GEO

Bulk RNA sequencing of livers from high fat diet plus carbon tetrachloride challenged Chrna2 fl/fl and Chrna2 fl/fl;AlbCre mice.

Project description:Loss of Chrna2 in the hepatocytes exacerbates the development of Metabolic dysfunction-associated steatohepatitis.

2024-06-07 | GSE264690 | GEO

Transcriptomic profiling of Hnf4a liver knockout mice (AlbCre-Hnf4a fl/fl) vs control (Hnf4a fl/fl) mice.

Project description:Transcriptomic profiling of Hnf4a liver knockout mice (AlbCre-Hnf4a fl/fl) vs control (Hnf4a fl/fl) mice.

| PRJNA796492 | ENA

Naïve and LCMV Cl13 infected liver tissue of ERT2 AlbCre Ifnar1 fl/fl mice

Project description:Naïve and LCMV Cl13 infected liver tissue of ERT2 AlbCre Ifnar1 fl/fl mice

| PRJNA481515 | ENA

Analysis of difference in transcriptome of Th2 cells derived from Gata3(fl/fl) and Klrg1Cre Gata3(fl/fl) mice

Project description:Purpose: To analyze the transcriptome difference of Th2 cells derived from Gata3(fl/fl) and Klrg1Cre Gata3(fl/fl) mice Method: Lung Th2 cells were used from mice chronically challenged with papain (40 µg/20 µl PBS, 6 subsequent papain challenges, day 0, 1, 2, 13, 14, and 15)

2024-02-01 | GSE166600 | GEO

Profiling of hepatic progenitor cells isolated from Egfr fl/fl and Met fl/fl murine control livers

Project description:Transcriptomic profiling; Determination of the transcriptomic similarity between Egfr fl/fl and Met fl/fl progenitor cells isolated from excised livers (n=3, each)

2013-09-05 | GSE46981 | GEO

Profiling of hepatic progenitor cells isolated from Egfr fl/fl and Met fl/fl murine control livers

Project description:Transcriptomic profiling; Determination of the transcriptomic similarity between Egfr fl/fl and Met fl/fl progenitor cells isolated from excised livers (n=3, each) Profiling of hepatic progenitor cells

2013-09-05 | E-GEOD-46981 | biostudies-arrayexpress

Genome-wide analysis of gene expression of livers of wild type and IL-4/IL-13-/- mice after carbon tetrachloride-induced injury

Project description:Global analysis of differentially expressed genes of livers of wild type and IL-4/IL-13-/- two days after carbon tetrachloride treatment. Total RNA obtained from isolated livers from vehicle and carbon tetrachloride administered wild type and IL-4/IL-13-/- mice.

2013-06-05 | E-GEOD-45002 | biostudies-arrayexpress

Genome-wide analysis of gene expression of livers of wild type and IL-4/IL-13-/- mice after carbon tetrachloride-induced injury

Project description:Global analysis of differentially expressed genes of livers of wild type and IL-4/IL-13-/- two days after carbon tetrachloride treatment.

2013-06-05 | GSE45002 | GEO

Wild type mice (Trsp) vs Trsp-knockout mice (DTrsp) or A34 or G37L or G37H transgenic mice

Project description:Comparative analysis of gene expression in the liver of the Trsp-knockout mice (Trspfl/fl-AlbCre+/+) and A34 (Trspfl/fl-AlbCre+/+-A34t/t), G37L (Trspfl/fl-AlbCre+/+-G37t/t; 2 copies), G37H (Trspfl/fl-AlbCre+/+-G37t/t; 16 copies) transgenic mice with gene expression of wild type mice (Trsp+/+-AlbCre+/+). Sec (selenocysteine) is biosynthesized on its tRNA and incorporated into selenium-containing proteins (selenoproteins) as the 21st amino acid residue. Selenoprotein synthesis is dependent on Sec tRNA and the expression of this class of proteins can be modulated by altering Sec tRNA expression. The gene encoding Sec tRNA (Trsp) is a single-copy gene and its targeted removal in liver demonstrated that selenoproteins are essential for proper function wherein their absence leads to necrosis and hepatocellular degeneration. In the present study, we found that the complete loss of selenoproteins in liver was compensated for by an enhanced expression of several phase II response genes and their corresponding gene products. The replacement of selenoprotein synthesis in mice carrying mutant Trsp transgenes, wherein housekeeping, but not stress-related selenoproteins are expressed, led to normal expression of phase II response genes. Thus the present study provides evidence for a functional link between housekeeping selenoproteins and phase II enzymes.

2008-08-19 | GSE12495 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data