Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single cell RNAseq profiling of Human Pancreatic Islets across sex

ABSTRACT: Single cell RNAseq profiling of Human Pancreatic Islets across sex

PROVIDER: PRJNA1106513 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR28850911.fastq.gz	Fastqsanger.gz
	SRR28850912.fastq.gz	Fastqsanger.gz
	SRR28850913.fastq.gz	Fastqsanger.gz
	SRR28850914.fastq.gz	Fastqsanger.gz
	SRR28850915.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 27

Similar Datasets

Single cell RNAseq profiling of Human Pancreatic Islets across sex

Project description:Mechanisms driving sex differences across islet cells is unknown. Thus, studying sex differences in islet regulation and function represent a unique avenue to understand the sex-specific heterogeneity in β cell failure in diabetes. We examined sex and race differences in human pancreatic islets from 15 donors using an orthogonal series of experiments including single cell RNA-seq (scRNA-seq), single nucleus assay for transposase-accessible chromatin sequencing (snATAC-seq), dynamic hormone secretion, and bioenergetics.

2024-07-25 | GSE266291 | GEO

Single nuclei ATACseq profiling of Human Pancreatic Islets across sex

2024-07-25 | GSE266405 | GEO

Single nuclei ATACseq profiling of Human Pancreatic Islets across sex

Project description:Single nuclei ATACseq profiling of Human Pancreatic Islets across sex

| PRJNA1106977 | ENA

Analysis of sex differences in DNA methylation in human pancreatic islets

Project description:Epigenetic factors regulate tissue-specific expression and X-chromosome inactivation. Previous studies have identified epigenetic differences between sexes in some human tissues. However, it is unclear whether epigenetic modifications contribute to sex-specific differences in insulin secretion and metabolism. In this study, we investigated the impact of sex on the genome-wide DNA methylation pattern in human pancreatic islets from 53 males and 34 females, and related the methylome to changes in expression and insulin secretion. 53 male and 34 female human pancreatic islet samples. Normally methylated, non-methylated and fully methylated human DNA samples were included as controls

2014-10-24 | E-GEOD-62640 | biostudies-arrayexpress

Global transcriptomic analysis of human pancreatic islets [RNAseq]

Project description:Global transcriptomic analysis of human pancreatic islets [RNAseq]

| PRJNA422401 | ENA

Analysis of sex differences in DNA methylation in human pancreatic islets

2014-10-24 | GSE62640 | GEO

Ring1b profiling in pancreatic islets

Project description:To gain insights into how pancreatic cells are programmed in vivo, we profiled Ring1b in embryonic stem cells and pancreatic islets

2013-01-04 | E-MTAB-1402 | biostudies-arrayexpress

Ring1b profiling in pancreatic islets

Project description:To gain insights into how pancreatic cells are programmed in vivo, we profiled RNA expression in pancreatic islets of pancreatic Ring1b conditional KO mice (conditional using a pancreas specfic Cre; Pdx1-Cre) and their littermate controls

2013-02-10 | E-MTAB-1404 | biostudies-arrayexpress

Effect of systemic adipsin overexpression on db/db mouse pancreatic islets

Project description:RNAseq of pancreatic islets of db/db mice treated with AAV- Adipsin vs AAV-GFP 4 weeks post AAV injection

2020-02-04 | GSE144575 | GEO

Sin3A mutant pancreatic islets

Project description:Sin3A mutant pancreatic islets

| PRJNA610630 | ENA