Project description:This is a deep targeted sequencing of human peripheral blood B cells and Germline control for lymphoma recurrently mutated genes using custom targeted panel using MIPs in duplicates
Project description:We use NGS to assess the ability of TALE-guided DNA methyltranferases to make targeted changes to DNA methylation Targeted bisulfite sequencing of cells infected with wild-type or mutant TALE-DNMT constructs directed to the CDKN2A (p16) locus