Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: GSK3 inhibition reduces ECM production and prevents age-related macular degeneration-like pathology

PROVIDER: PRJNA1123278 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR29384174_1.fastq.gz	Fastqsanger.gz
	SRR29384174_2.fastq.gz	Fastqsanger.gz
	SRR29384175_1.fastq.gz	Fastqsanger.gz
	SRR29384175_2.fastq.gz	Fastqsanger.gz
	SRR29384176_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

To measure extension longevity effect of soraprazan and identify the mechanism

Project description:Lipofuscin is known as intracellular waste substance produced by damaged mitochondrial incompleted decomposition. And it is a biomarker of aging. As aging, accumulation of the lipofuscin in retinal pigment epithelium induces blindness called Age-related macular degeneration. Soraprazan is developed to reduce the lipofuscin production and cure the age-related macular degeneration. Soraprazan reducing the age biomarker lipofuscin can be suggested to have effect of longevity extension. C.elegans were treated on NGM agar plate containing 0, 50, 100, 200 μM soraprazan and showed the lipofuscin reduction and extension of longevity. To identify the mechanism, 0 and 200 μM treated worms’ RNA expression was analyzed through microarray.

2020-01-23 | GSE144059 | GEO

Whole genome methylation profiling of the retinal pigment epithelium of individuals with age-related macular degeneration

Project description:Illumina Infinium HumanMethylation450 BeadChip data from genomic DNA of retinal pigment epithelium from Age-related Macular Degeneration patients or age-matched controls.

2019-08-01 | E-MTAB-7183 | biostudies-arrayexpress

Homo sapiens

Project description:NEI:Age Related Macular Degeneration at CIDR

| PRJNA76053 | ENA

human eye metagenome

Project description:Infectious Etiology of Age-related Macular Degeneration

| PRJNA429692 | ENA

Homo sapiens

Project description:NEI:Age Related Macular Degeneration at CIDR

| PRJNA76055 | ENA

Project description:CRISPR-LbCpf1 prevents choroidal neovascularization in a mouse model of age-related macular degeneration

| PRJNA430142 | ENA