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To identify differentially expressed genes in ventricular tissue between wildtype control and the 6-month-old mtorxu015/+ mutant, Tg(cmlc2:tfeb) transgenic zebrafish at six months.

ABSTRACT: To identify differentially expressed genes in ventricular tissue between wildtype control and the 6-month-old mtorxu015/+ mutant, Tg(cmlc2:tfeb) transgenic zebrafish at six months.

PROVIDER: PRJNA1123307 | ENA |

REPOSITORIES: ENA

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			Action	DRS
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	SRR29382474_1.fastq.gz	Fastqsanger.gz
	SRR29382474_2.fastq.gz	Fastqsanger.gz
	SRR29382476_1.fastq.gz	Fastqsanger.gz
	SRR29382476_2.fastq.gz	Fastqsanger.gz

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To identify differentially expressed genes in ventricular tissue between wildtype control and the 6-month-old mtorxu015/+ mutant, Tg(cmlc2:tfeb) transgenic zebrafish at six months.

Project description:To seek molecular mechanisms underlying the mechanisms of mutant genotypes by comparing them witht he wild types, we performed whole transcriptome RNA-sequencing experiments using ventricular tissue isolated from 6-month-old mtorxu015/+ mutant, Tg(cmlc2:tfeb) transgenic zebrafish,and corresponding WT siblings.

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TFEB activation in macrophages attenuates postmyocardial infarction ventricular dysfunction independently of ATG5-mediated autophagy

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TFEB activation in macrophages attenuates postmyocardial infarction ventricular dysfunction independently of ATG5-mediated autophagy

Project description:TFEB activation in macrophages attenuates postmyocardial infarction ventricular dysfunction independently of ATG5-mediated autophagy

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Expression data from injected mice overexpressing TFEB specifically in liver

Project description:In order to identify the effects of transcription factor EB (TFEB) overexpression on the liver transcriptome, we performed Affymetrix GeneChip hybridization experiments on injected mice overexpressing TFEB specifically in the liver. For the analysis of the injected mice overexpressing TFEB, total RNA was extracted from the liver of three mice. RNA extracted from the liver of 3 not-injected mice was used as a control.

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