Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Effects of high cholesterol diet on liver small RNA expression profile utilizing two different RNA-seq methods

ABSTRACT: Effects of high cholesterol diet on liver small RNA expression profile utilizing two different RNA-seq methods

PROVIDER: PRJNA1131393 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Effects of high cholesterol diet on sperm small RNA expression profile utilizing two different RNA-seq methods

Project description:Purpose: To reveal the small RNA profiles in the sperm using traitional and PANDORA-seq methods Methods: 3 week old LDLR-/- male mice were fed a high cholesterol or low cholesterol diet for 9 weeks. Sperm RNA was extracted via Trizol. Results: paternal HCD feeding can lead to sperm tsRNA/rsRNA landscape changes that are undetected by traditional RNA-seq

2024-10-08 | GSE251712 | GEO

Effects of high cholesterol diet on sperm small RNA expression profile utilizing two different RNA-seq methods

Project description:Effects of high cholesterol diet on sperm small RNA expression profile utilizing two different RNA-seq methods

| PRJNA1055102 | ENA

Effects of high cholesterol diet on liver small RNA expression profile utilizing two different RNA-seq methods

Project description:Purpose: To reveal the small RNA profiles in the liver using traitional and PANDORA-seq methods Methods: 8 week old C57BL/6 male mice were fed a high cholesterol or low cholesterol diet for 4 weeks. Liver RNA was extracted by injecting Trizol into the aorta and collecting the flow through for further processing Results: PANDORA-seq revealed an abundant amount of tsRNA and rsRNA that were undetected by traditional-seq. Importantly, PANDORA-seq revealed that many differentially regulated sncRNAs also undetected with traditional-seq

2025-07-02 | GSE271436 | GEO

Effects of high cholesterol diet on intimal small RNA expression profile utilizing two different RNA-seq methods [Intima_small_RNA]

Project description:Purpose: To reveal the small RNA profiles in the intima using traditional and PANDORA-seq methods. Methods: 3-week-old LDLR-/- male mice were fed a high cholesterol or low cholesterol diet for 9 weeks. Intimal RNA was extracted by injecting Trizol into the aorta and collecting the flow through for further processing. Results: PANDORA-seq revealed an abundant amount of tsRNA and rsRNA that were undetected by traditional-seq. Importantly, PANDORA-seq revealed that many differentially regulated sncRNAs also undetected with traditional-seq.

2023-02-08 | GSE213304 | GEO

Effects of high cholesterol diet on intimal small RNA expression profile utilizing two different RNA-seq methods [Intima_small_RNA]

Project description:Effects of high cholesterol diet on intimal small RNA expression profile utilizing two different RNA-seq methods [Intima_small_RNA]

| PRJNA880420 | ENA

Effects of DCHP exposure on sperm small RNA expression profile utilizing two different RNA-seq methods

Project description:Effects of DCHP exposure on sperm small RNA expression profile utilizing two different RNA-seq methods

| PRJNA890632 | ENA

Effects of DCHP exposure on sperm small RNA expression profile utilizing two different RNA-seq methods

Project description:Purpose: To reveal the small RNA profiles in the sperm using traitional and PANDORA-seq methods Methods: 8 week male WT mice were exposed to DCHP by oral gavage for 4 weeks. Sperm RNA was extracted for further processing Results: PANDORA-seq revealed an abundant amount of tsRNA and rsRNA that were undetected by traditional-seq. Importantly, PANDORA-seq revealed that many differentially regulated sncRNAs also undetected with traditional-seq

2023-05-24 | GSE215804 | GEO

Effects of high cholesterol diet on intimal transcriptome [Intima_mRNA]

Project description:Purpose: To investigate the effects of high cholesterol diet on the intimal transcriptome related to atherosclerosis. Methods: 3-week-old LDLR-/- male mice were fed a high cholesterol or low cholesterol diet for 9 weeks. Intimal RNA was extracted by injecting Trizol into the aorta and collecting the flow through for further processing. Results: Mice fed a high cholesterol revealed upregulation in atherosclerosis and immune/inflammatory related genes.

2023-02-08 | GSE213303 | GEO

RNA-Seq of rabbits treated with normal diet or high cholesterol diet

Project description:We fed PGC1-alpha (mouse gene) transgenic rabbits and control rabits with normal diet or high cholesterol diet. Then we extract RNA from their vascular cells and performed RNA-Seq comapre the expression level of the mRNAs.

2021-06-08 | GSE176340 | GEO

Effects of paternal high cholesterol diet on F1 generation intimal transcriptome

Project description:Purpose: To investigate the effects of paternal high cholesterol diet on the F1 intimal transcriptome related to atherosclerosis. Methods:Three-week-old male LDL Receptor-deficient (LDLR-/-) male mice were fed a low-cholesterol diet (LCD) or high-cholesterol diet (HCD) for 8 weeks and then mated with age-matched control LDLR-/- female mice to generate F1 offspring. F1 LDLR-/- mice were fed a LCD for 16 weeks. Intimal RNA was extracted by injecting Trizol into the aorta and collecting the flow through for further processing. Results: . Total RNA isolated from the F1 intima were then subjected for RNA-sequencing analysis and results show that paternal hypercholesterolemia led to upregulation of 147 genes in the intimal of F1 female mice, many of which are involved in immune and inflammatory pathways.

2024-10-08 | GSE251711 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data