Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Microbiome diversity in partial denitrification system

PROVIDER: PRJNA1135935 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR29830258.fastq.gz	Fastqsanger.gz
	SRR29830259.fastq.gz	Fastqsanger.gz
	SRR29830260.fastq.gz	Fastqsanger.gz
	SRR29830261.fastq.gz	Fastqsanger.gz
	SRR29830262.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 5

Similar Datasets

Project description:partial denitrification

| PRJNA634713 | ENA

Project description:partial denitrification

| PRJNA598501 | ENA

Project description:partial denitrification biofilm

| PRJNA1181936 | ENA

Morphine treatment induces distinct changes in the gut microbiome at day 3 post treatment

Project description:Opioids such as morphine have many beneficial properties as analgesics, however, opioids may induce multiple adverse gastrointestinal symptoms. We have recently demonstrated that morphine treatment results in significant disruption in gut barrier function leading to increased translocation of gut commensal bacteria. However, it is unclear how opioids modulate the gut homeostasis. By using a mouse model of morphine treatment, we studied effects of morphine treatment on gut microbiome. We characterized phylogenetic profiles of gut microbes, and found a significant shift in the gut microbiome and increase of pathogenic bacteria following morphine treatment when compared to placebo. In the present study, wild type mice (C57BL/6J) were implanted with placebo, morphine pellets subcutaneously. Fecal matter were taken for bacterial 16s rDNA sequencing analysis at day 3 post treatment. A scatter plot based on an unweighted UniFrac distance matrics obtained from the sequences at OTU level with 97% similarity showed a distinct clustering of the community composition between the morphine and placebo treated groups. By using the chao1 index to evaluate alpha diversity (that is diversity within a group) and using unweighted UniFrac distance to evaluate beta diversity (that is diversity between groups, comparing microbial community based on compositional structures), we found that morphine treatment results in a significant decrease in alpha diversity and shift in fecal microbiome at day 3 post treatment compared to placebo treatment. Taxonomical analysis showed that morphine treatment results in a significant increase of potential pathogenic bacteria. Our study shed light on effects of morphine on the gut microbiome, and its role in the gut homeostasis.

2018-04-16 | E-MTAB-5546 | biostudies-arrayexpress

Project description:Partial denitrification sludge sample

| PRJNA1000759 | ENA

Project description:Partial denitrification sludge sample

| PRJNA1194738 | ENA

Microbial communities in the simultaneous anammox and denitrification system and the partial denitrification and anammox system

Project description:Microbial communities in the simultaneous anammox and denitrification system and the partial denitrification and anammox system Raw sequence reads

| PRJNA782456 | ENA

Project description:autotrophic partial denitrification-anammox-bioelectrochemical system for ammonia and nitrate removal

| PRJNA1063630 | ENA

Project description:Microbial diversity in sulfur-based autotrophic denitrification system

| PRJNA1039589 | ENA

bioreactor metagenome

Project description:partial denitrification bacteria Targeted loci

| PRJNA377965 | ENA