Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq of wild-type and ZNF217-knockout KOPN-8 cells

ABSTRACT: RNA-seq of wild-type and ZNF217-knockout KOPN-8 cells

PROVIDER: PRJNA1136576 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR29849552_1.fastq.gz	Fastqsanger.gz
	SRR29849552_2.fastq.gz	Fastqsanger.gz
	SRR29849553_1.fastq.gz	Fastqsanger.gz
	SRR29849553_2.fastq.gz	Fastqsanger.gz
	SRR29849554_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

RNA-seq of wild-type and ZNF217-knockout KOPN-8 cells

Project description:Here, we demonstrate that ZNF217 plays an oncogenic role in B-ALL. To investigate the underlying mechanisms and pinpoint potential downstream targets that contribute to ZNF217's oncogenic role, we conducted high-throughput RNA-seq on both wild-type and ZNF217-knockout KOPN-8 cells. Our analysis revealed that FOS is An important target of ZNF217 in B-ALL.

2025-02-16 | GSE272398 | GEO

CUT&RUN sequencing of wild-type and ZNF217-knockdown KOPN-8 cells

Project description:Here, we elucidate the oncogenic role of ZNF217 in B-ALL and reveal that ZNF217 interacts with the CoREST complex to mediate histone modifications such as H3K4me1, H3K4me2, and H3K27ac. This interaction partially contributes to ZNF217’s oncogenic function in B-ALL. To identify genes directly bound by ZNF217, we conducted high-throughput CUT&RUN sequencing using an anti-ZNF217 antibody in both wild-type and ZNF217-knockdown KOPN-8 cells. Additionally, to distinguish between CoREST-dependent and CoREST-independent targets, we performed CUT&RUN sequencing in the same cell models using an antibody against LSD1, a core component of the CoREST complex that interacts with ZNF217, as well as antibodies against H3K4me1, H3K4me2, and H3K27ac.

2025-02-16 | GSE272397 | GEO

CUT&RUN sequencing of wild-type and ZNF217-knockdown KOPN-8 cells

Project description:CUT&RUN sequencing of wild-type and ZNF217-knockdown KOPN-8 cells

| PRJNA1136575 | ENA

E. Coli Nissle wild type versus knockout strain

Project description:E. Coli Nissle wild type versus knockout strain grown in M-9 media.

2019-01-31 | MSV000083387 | MassIVE

Analysis of wild-type and METTL5 knockout cells

Project description:Analysis of wild-type and METTL5 knockout cells

| PRJNA729788 | ENA

Mouse ES Cells: Wild type vs. Zscan5b knockout

Project description:Mouse ES Cells: Wild type vs. Zscan5b knockout