Ontology highlight
ABSTRACT:
PROVIDER: PRJNA1146871 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR30223800.fastq.gz | Fastqsanger.gz | |||
| SRR30223801.fastq.gz | Fastqsanger.gz | |||
| SRR30223802.fastq.gz | Fastqsanger.gz | |||
| SRR30223803.fastq.gz | Fastqsanger.gz | |||
| SRR30223804.fastq.gz | Fastqsanger.gz |
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Project description:Across Canada, infections associated with Fusarium have a devastating impact on the agricultural sector. For example, Fusarium head blight (FHB) costs the Canadian grain industry over $1.5 billion annually in diminished export and domestic sales. For Ontario’s most productive and lucrative crops infection by Fusarium spp., leads to losses of over $200 million annually through yield reduction in corn (i.e., stalk and ear rot), cereals (i.e., FHB), and soybeans (i.e., root rot and sudden death syndrome). Additionally, mycotoxin production by Fusarium spp. (e.g., deoxynivalenol [DON]) has severe consequences for the livestock and poultry industries through consumption of contaminated feed, as well as concerns for human health upon consumption of contaminated processed grains. Current management strategies against FHB rely on fungicide application at heading, which reduces infection but does not limit the accumulation of dangerous mycotoxins within the grains. Moreover, such fungicide applications substantially increase the economic cost to growers, raise public concerns over chemical exposure, and contribute to the development of antimicrobial resistance. The critical role of Fusarium fungal pathogens and their toxins in the health of crops, livestock, and humans underscores the need for innovative strategies to better understand mechanisms of disease and identify novel management strategies to limit the incidence of infection and to critically, reduce the accumulation of mycotoxins within infected grains
2022-09-27 | PXD037035 | Pride
Project description:Fusarium graminearum can infect maize stalk causing Gibberella stalk rot. We want to know the whole genome wide gene profiling when infecting maize stalk.
2016-02-11 | GSE53854 | GEO
Project description:The fungal pathogen Fusarium moniliforme causes ear rot in maize. Ear rot in maize is a destructive disease globally caused by Fusarium moniliforme , due to decrease of grain yield and increase of risks in raising livestock by mycotoxins production. Plants have developed various defense pathways to cope with pathogens. We used microarrays to detail the global programme of gene expression during the infection process of Fusarium moniliforme in its host plant to get insights into the defense programs and the host processes potentially involved in plant defense against this pathogen.
2009-12-16 | GSE19501 | GEO
Project description:Fusarium graminearum can infect maize stalk causing Gibberella stalk rot. We want to know the whole genome wide gene profiling when infecting maize stalk. Using lasr capture microdisecction, we captured 8 time points infecting hyphae samples for maize stalk and after two-round amplification, we hybrid the aRNA to Affymetrix array.
2016-02-11 | E-GEOD-53854 | biostudies-arrayexpress
Project description:The fungal pathogen Fusarium moniliforme causes ear rot in maize. Ear rot in maize is a destructive disease globally caused by Fusarium moniliforme , due to decrease of grain yield and increase of risks in raising livestock by mycotoxins production. Plants have developed various defense pathways to cope with pathogens. We used microarrays to detail the global programme of gene expression during the infection process of Fusarium moniliforme in its host plant to get insights into the defense programs and the host processes potentially involved in plant defense against this pathogen. Experiment Overall Design: In two compared independent experiments plants were infected with the Fusarium moniliforme. Samples from infected bracts of resistant maize (Bt-1) as well as susceptible maize (Ye478) were taken at 4 days post infection. Samples from uninfected control plants were taken at the same time points. For example: R0 (control) and RT (treat) in Bt-1 and S0 (control) and ST (treat) in Ye478.
2010-01-19 | E-GEOD-19501 | biostudies-arrayexpress
Project description:Identify genes underlying the Fusarium crown rot resistance locus and find out if expressed genes associated with resistance to Fusarium crown rot were related to those observed by others for Fusarium head blight.
2015-10-15 | E-MTAB-4308 | biostudies-arrayexpress
Project description:Fusarium spp. are fungal pathogens of humans and plants. Fusarium oxysporum and Fusarium solani are important species isolated from infections such as onychomycosis, fungal keratitis, invasive infections, and disseminated diseases. These pathologies have a very difficult therapeutic management and poor therapeutic responses, especially in patients with disseminated infection. Little information is available regarding the molecular mechanisms responsible for antifungal resistance in these fungi. methods: In this study, we performed a quantitative analysis of the transcriptional profile of F. oxysporum and F. solani, challenged with amphotericin B (AMB) and posaconazole (PSC) using RNA-seq. Quantitative real-time reverse transcription PCR (qRT-PCR) was used to validate the results results: Several genes related to mechanisms of antifungal resistance such as efflux pumps, ergosterol pathway synthesis, and responses to oxidative stress were found. Genes such as ERG11, ERG5, the Major Facilitator Superfamily (MFS), thioredoxin, and different dehydrogenase genes may explain the reduced susceptibility of Fusarium spp. against azoles and the possible mechanisms that may play an important role in induced resistance against polyenes. conclusions: Important differences in the levels of transcriptional expression were found between F. oxysporum and F. solani exposed to the two different antifungal treatments. Knowledge on the gene expression profiles and gene regulatory networks in Fusarium spp. during exposure to antifungal compounds, may help to identify possible molecular targets for the development of novel, better, and more specific therapeutic compounds. profile transcriptional of Fusarium spp changed to antifungal treatments in vitro
2016-06-01 | E-GEOD-82060 | biostudies-arrayexpress
Project description:Effect of Potato Glycoside Alkaloids on Mitochondria Energy Metabolism of Fusarium solani, the Root Rot Pathogen of Lycium Barbarum.
2024-12-16 | PXD058927 |