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Limosilactobacillus reuteri subsp. kinnaridis strain:DSM 17938

ABSTRACT: Limosilactobacillus reuteri subsp. kinnaridis strain:DSM 17938 Genome sequencing

PROVIDER: PRJNA1153401 | ENA |

REPOSITORIES: ENA

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Proteomic analysis of Limosilactobacillus reuteri DSM 17938

Project description:The aim of this work was to assess the antibiofilm activity of Cell Free Supernatant (CFS) produced by Limosilactobacillus reuteri DSM 17938 versus biofilm-producer bacterial species of clinical relevance.

2025-06-09 | PXD035326 | Pride

Gene expression comparison of L. reuteri DSM 17938 and pocR mutant

2014-01-24 | GSE54324 | GEO

Gene expression comparison of L. reuteri DSM 17938 and pocR mutant

Project description:Comparison of gene expression between L. reuteri DSM 17938 and L. reuteri DSM 17938::pocR mutant grown in semi-defined medium after 24h of growth at 37C in anaerobic condition. PocR is an AraC-like transcriptional regulator, and changes in gene expression between mutant and wild-type strains would indicate genes involved in the PocR regulon. Includes 3 biological replicates and dye-swaps for DSM 17938 versus pocR mutant. One sample includes total RNA isolated from wildtype DSM 17938 labeled with either cy3 or cy5, and total RNA isolated from the pocR mutant labeled with the opposite dye. Samples 1, 2, and 3 represent biological replicates. Samples 4, 5, and 6 represent dye-swaps of the same biological replicates.

2014-01-24 | E-GEOD-54324 | biostudies-arrayexpress

Limosilactobacillus reuteri subsp. reuteri strain:DSM 20016

Project description:Limosilactobacillus reuteri subsp. reuteri strain:DSM 20016 Raw sequence reads

| PRJNA297938 | ENA

Limosilactobacillus reuteri-derived exopolysaccharides facilitate the repair of intestinal epithelium barrier compromised by chemotherapy exposure

Project description:A majority of patients undergoing chemotherapy treatment develop side effects that delay further cancer treatment. Antimetabolites, like 5 Fluorouracil (5 FU), are known to induce gut and oral inflammation, highlighting the importance of chemotherapy toxicity management. Here, we aimed to study whether probiotic bacterium Limosilactobacillus reuteri DSM 17938 (LR)-secreted components, including cell-free supernatant (CFS), exopolysaccharides (EPS), and extracellular membrane vesicles (MV), can improve gut barrier integrity following 5 FU exposure. Collectively, 5 FU altered the viability, metabolic activity, barrier integrity, and functional response of Caco-2 cells. EPS stimulation after 5 FU removal significantly improved the integrity and permeability of intestinal barrier through modulation of the transcriptional program associated with extracellular matrix and structure organization. Further, we found that CFS, MV and EPS differentially influenced monocyte polarization pathways, when monocytes were cultured with the supernatant from 5 FU exposed Caco-2 cells. Together, our findings suggest that the incorporation of bacterial metabolites, such as EPS, during chemotherapy could accelerate intestinal barrier recovery without suppressing the immune system, potentially allowing for a more effective scheduling of therapy in cancer patients.

2026-04-17 | GSE288972 | GEO

Limosilactobacillus reuteri

Project description:Lactobacillus reuteri DSM 17938 modulates gut microbiota in newborn mice

| PRJNA399746 | ENA

Limosilactobacillus reuteri subsp. kinnaridis strain:BG-R46

Project description:Limosilactobacillus reuteri subsp. kinnaridis strain:BG-R46 (DSM 32846) Genome sequencing

| PRJNA1153400 | ENA

Transcriptome analysis of collagen-adhered S. gallolyticus subsp. gallolyticus [DSM 16831]

Project description:Streptococcus gallolyticus subsp. gallolyticus is a commensal of the human gastrointestinal tract and a pathogen of infective endocarditis and other biofilm-associated infections with exposed collagen. Therefore, this study focuses on the characterization of the biofilm formation and collagen adhesion of S. gallolyticus subsp. gallolyticus under different conditions. It has been observed that lysozyme triggers biofilm formation divergently in the analyzed S. gallolyticus subsp. gallolyticus strains. The transcriptome analysis was performed for two strains which form more biofilm in the presence of lysozyme. Lysozyme leads to higher expression of genes of transcription and translation, of the dlt operon (cell wall modification), of hydrogen peroxide resistance proteins and of two immunity proteins which could be involved in biofilm formation. Furthermore, the adhesion ability of 73 different S. gallolyticus subsp. gallolyticus strains to collagen type I and IV was analyzed. High adhesion ability was observed for the strain UCN 34, whereas the strain DSM 16831 adhered only marginally to collagen. The full genome microarray analysis revealed strain-dependent gene expression due to adhesion. The expression of genes of a transposon and a phage region in strain DSM 16831 were increased, which corresponds to lateral gene transfer. Adherence to collagen leads to a change in the expression of genes of nutrients uptake in the strain UCN 34.

2017-05-17 | GSE98953 | GEO

Limosilactobacillus reuteri

Project description:Gene expression comparison of L. reuteri DSM 17938 and pocR mutant

| PRJNA236182 | ENA

Expression of stress responsive genes enables Limosilactobacillus reuteri

Project description:Expression of stress responsive genes enables Limosilactobacillus reuteri to cross-protection against acid, bile salt and freeze-drying

2023-11-03 | PXD046687 |

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