Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Insulin mitigates acute ischemia induced atrial fibrillation and sinoatrial node dysfunction ex vivo

ABSTRACT: Insulin mitigates acute ischemia induced atrial fibrillation and sinoatrial node dysfunction ex vivo

PROVIDER: PRJNA1172142 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR30970545_1.fastq.gz	Fastqsanger.gz
	SRR30970545_2.fastq.gz	Fastqsanger.gz
	SRR30970546_1.fastq.gz	Fastqsanger.gz
	SRR30970546_2.fastq.gz	Fastqsanger.gz
	SRR30970547_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 32

Similar Datasets

Insulin mitigates acute ischemia induced atrial fibrillation and sinoatrial node dysfunction ex vivo

Project description:Acute atrial ischemia is a well-known cause of postoperative atrial fibrillation (POAF). However, the cellular and electrophysiological mechanisms through which ischemia contributes to the development of POAF are not well understood. Administering insulin 30 minutes before ischemia and during reperfusion with 25 minutes of ischemia greatly reduced the vulnerability to AF.

2024-11-14 | GSE279356 | GEO

Atrial Fibrillation After Surgery for Colorectal Cancer

Project description:This study will report the incidence of atrial fibrillation after elective colorectal cancer resection in the over 65 age group. This will be used to validate a risk model for the development of post-operative atrial fibrillation. Eligible patients will undergo electrocardiogram based screening for atrial fibrillation, as well as brain natriuretic peptide tests prior to surgery. They will undergo 24 hour holter monitor prior to surgery, and at 30 and 90 days following surgery. The primary outcome will be occurrence of atrial fibrillation within 90 days of surgery. Secondary outcomes include quality of life change, use of hospital services for atrial fibrillation, and complications of atrial fibrillation. This will be used to validate the pre-existing model for prediction of atrial fibrillation.

| 2312263 | ecrin-mdr-crc

The ERBB4 agonist JK07 Mitigates Atrial Remodeling and Inducibility of Atrial Fibrillation in Mice and Minipigs

Project description:To establish changes in cardiomyocyte transcription profiles brought about by atrial fibrillation, we collected left atrial appendage samples from minipig induced by DOCA or DOCA and JK07 and from vehicle samples. The transcriptional profile of mRNA in these samples will be measured with high throughput technology. Changes in transcriptional profiles can be correlated with the physiologic profile of atrial fibrillation acquired at the time of harverst.

2025-03-01 | GSE255166 | GEO

Atrial Fibrillation Patient's Urine miRNA Microarray

Project description:Analysis for early diagnosis of atrial fibrillation by finding changes in miRNA in the urine of patients with atrial fibrillation

2021-12-16 | GSE190898 | GEO

Regional transcriptomics of a human left atrium and implications for atrial fibrillation

Project description:Regional differential expression of atrial fibrillation risk genes in the left atrium and pulmonary veins is not well studied, but may yield insights into atrial fibrillation pathogenesis. We tested the hypothesis that there is significant regional differential expression in left atrium structures. RNAseq was performed in 25 regions within the pulmonary veins (n=12), left atrial body (n=10), and left atrial appendage (n=3) from a 75 year old male with hypertension and atrial fibrillation who died of a stroke. These data show that genes involved in atrial fibrillation pathogenesis have substantial regional expression heterogeneity, particularly when comparing the left atrial body, pulmonary veins and left atrial appendage.

2020-11-14 | GSE161450 | GEO

Comparison of atrial appendage tissues of patients with Valvular Heart Disease and patients with Valvular Heart Disease-Atrial Fibrillation

Project description:Atrial fibrillation (AF) is the most common heart arrhythmia disease. The greatest risk of atrial fibrillation is stroke, and stroke caused by valvular heart disease with atrial fibrillation (AF-VHD) is more serious. the development mechanism from VHD to AF-VHD is not yet clear. The research on expression profiles of lncRNA and mRNA is helpful to explore molecular mechanism in patients with valvular heart disease who develop atrial fibrillation.

2018-04-12 | GSE113013 | GEO

Comparative Gene Expression During Sinoatrial Node and Atrial Development

Project description:To determine pathways activated during sinoatrial node morphogenesis we conducted bulk RNA sequencing on functionally validated tissue preps of embryonic sinoatrial node and atria.

2023-03-22 | GSE227027 | GEO

Ibrutinib-mediated atrial fibrillation

Project description:Ibrutinib-mediated atrial fibrillation

| PRJNA579694 | ENA

Gene expression and atrial fibrillation prediction

Project description:The aim of this study was to identify a blood gene expression profile that predicts atrial fibrillation in heart failure patients

2024-06-24 | GSE235307 | GEO

The ERBB4 agonist JK07 Mitigates Atrial Remodeling and Inducibility of Atrial Fibrillation in Mice and Minipigs

Project description:The ERBB4 agonist JK07 Mitigates Atrial Remodeling and Inducibility of Atrial Fibrillation in Mice and Minipigs

| PRJNA1074095 | ENA