Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Enterobacteriaceae bacterium strain:entHe1

ABSTRACT: An obligate symbiont of Haematomyzus elephantis

PROVIDER: PRJNA1173735 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR31123095_1.fastq.gz	Fastqsanger.gz
	SRR31123095_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 3 of 3

Similar Datasets

Whole Genome Metabolism - Enterobacteriaceae bacterium (strain FGI 57)

Project description: Not available

| BMID000000142321 | biostudies-other

Nanoarchaeum equitans Kin4-M

Project description:Hyperthermophilic anaerobic obligate symbiont

| PRJNA9599 | ENA

Candidatus Amoebophilus asiaticus 5a2

Project description:Obligate symbiont of a free-living amoeba

| PRJNA19981 | ENA

Host cell-free growth of the Q fever bacterium Coxiella burnetii

Project description:The inability to propagate obligate intracellular pathogens under axenic (host cell-free) culture conditions imposes severe experimental constraints that have negatively impacted progress in understanding pathogen virulence and disease mechanisms. Coxiella burnetii, the causative agent of human Q (Query) fever, is an obligate intracellular bacterial pathogen that replicates exclusively in an acidified, lysosome-like vacuole. To define conditions that support C. burnetii growth, we systematically evaluated the organism’s metabolic requirements using expression microarrays, genomic reconstruction, and metabolite typing. This led to development of a complex nutrient medium that supported substantial growth (~ 3 log10) of C. burnetii in a 2.5% oxygen environment. Importantly, axenically grown C. burnetii were highly infectious for Vero cells and exhibited developmental forms characteristic of in vivo grown organisms. Axenic cultivation of C. burnetii will facilitate studies of the organism’s pathogenesis and genetics, and aid development of Q fever preventatives such as an effective subunit vaccine. Furthermore, the systematic approach used here may be broadly applicable to development of axenic media that support growth of other medically important obligate intracellular pathogens.

2009-10-21 | GSE13338 | GEO

Host cell-free growth of the Q fever bacterium Coxiella burnetii

Project description:The inability to propagate obligate intracellular pathogens under axenic (host cell-free) culture conditions imposes severe experimental constraints that have negatively impacted progress in understanding pathogen virulence and disease mechanisms. Coxiella burnetii, the causative agent of human Q (Query) fever, is an obligate intracellular bacterial pathogen that replicates exclusively in an acidified, lysosome-like vacuole. To define conditions that support C. burnetii growth, we systematically evaluated the organismâ??s metabolic requirements using expression microarrays, genomic reconstruction, and metabolite typing. This led to development of a complex nutrient medium that supported substantial growth (~ 3 log10) of C. burnetii in a 2.5% oxygen environment. Importantly, axenically grown C. burnetii were highly infectious for Vero cells and exhibited developmental forms characteristic of in vivo grown organisms. Axenic cultivation of C. burnetii will facilitate studies of the organismâ??s pathogenesis and genetics, and aid development of Q fever preventatives such as an effective subunit vaccine. Furthermore, the systematic approach used here may be broadly applicable to development of axenic media that support growth of other medically important obligate intracellular pathogens. Host cell-free growth, Vero cell growth and carryover baseline of Coxiella burnetii

2010-06-20 | E-GEOD-13338 | biostudies-arrayexpress

Enterobacteriaceae bacterium

Project description:Identification of MCR-8 in clinical isolates from Qatar and evaluation of their antimicrobial profiles

| PRJNA609881 | ENA

Enterobacteriaceae bacterium

Project description:Enterobacteriaceae bacterium Genome sequencing and assembly

| PRJNA1247454 | ENA

Enterobacteriaceae bacterium

Project description:Enterobacteriaceae bacterium overview

| PRJNA492587 | ENA

Enterobacteriaceae bacterium

Project description:Enterobacteriaceae bacterium Genome sequencing and assembly