Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

A unified molecular approach for spatial epigenome, transcriptome, and cell lineages

ABSTRACT: A unified molecular approach for spatial epigenome, transcriptome, and cell lineages

PROVIDER: PRJNA1174228 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR31034020_1.fastq.gz	Fastqsanger.gz
	SRR31034020_2.fastq.gz	Fastqsanger.gz
	SRR31034021_1.fastq.gz	Fastqsanger.gz
	SRR31034021_2.fastq.gz	Fastqsanger.gz
	SRR31034022_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 8

Similar Datasets

A unified molecular approach for spatial epigenome, transcriptome, and cell lineages

Project description:Spatial epigenomics and multiomics can provide fine-grained insights into cell state but widespread adoption is limited by the requirement for bespoke slides and capture chemistries for each data modality. Here, we develop an approach (SPACE-seq) that uses a transposome with polyadenine adaptors to generate polyA-tailed epigenomic libraries, enabling facile spatial epigenomics and multiomics using standard whole transcriptome reagents. Application of SPACE-seq to a human glioblastoma specimen defines the spatial localization and accessible chromatin of distinct sub-populations within the tumor, and putative mitochondrial DNA variants.

2025-01-23 | GSE279771 | GEO

Spatial epigenome-transcriptome co-profiling of mammalian tissues [spatial CUT&Tag]

Project description:We present spatially resolved high-spatial-resolution genome-wide co-mapping of epigenome and transcriptome by simultaneously profiling of chromatin accessibility and gene expression (spatial-ATAC-RNA-seq), as well as histone modification and gene expression (spatial-CUT&Tag-RNA-seq) on the same tissue section at cellular level by combining the microfluidic deterministic barcoding strategy in DBiT-seq and the chemistry used in ATAC-seq/CUT&Tag.

2023-01-29 | GSE217091 | GEO

Spatial epigenome-transcriptome co-profiling of mammalian tissues [spatial CUT&Tag]

Project description:Spatial epigenome-transcriptome co-profiling of mammalian tissues [spatial CUT&Tag]

| PRJNA896927 | ENA