Project description:Urine miRNA signature as potential non-invasive diagnostic biomarker for Hirschsprung’s Disease (HSCR): Unfortunately, HSCR diagnosis remains a challenge: current diagnostic methods are too invasive and difficult to conduct and to interpret. We designed this study in urine with the aim of identifying a non-invasive biomarker, which undoubtfully, would be a more convenient method for both babies and parents in the future.