Project description:ChIP-seq analyses were carried out in intestinanl epithelial cells (IECs) isolated from F/FUN and ΔIECUN mice to assess histone modifications across the genome, an event that links the actions of corepressors with molecular insight towards a mechanism.
Project description:To explore the molecular events engaged following the deletion of NCoR1 in intestinal tissue during development, we performed global transcriptional profiling in wild type (F/FUN) and NCoR1 intestinal deletion (ΔIECUN) mice at neonates (day 12) and adults (week 10) by utilizing RNA-seq technology.