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Tetrahymena thermophila

ABSTRACT: Methyl-dependent auto-regulation of the DNA N6-adenine methyltransferase AMT1 in the unicellular eukaryote Tetrahymena thermophila

PROVIDER: PRJNA1193833 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR31602620_1.fastq.gz	Fastqsanger.gz
	SRR31602620_2.fastq.gz	Fastqsanger.gz
	SRR31602621_1.fastq.gz	Fastqsanger.gz
	SRR31602621_2.fastq.gz	Fastqsanger.gz
	SRR31602622_1.fastq.gz	Fastqsanger.gz

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Tetrahymena thermophila

Project description:Methyl-dependent auto-regulation of the DNA N6-adenine methyltransferase AMT1 in the unicellular eukaryote Tetrahymena thermophila

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Project description:In endolysosomal networks, two hetero-hexameric tethers called HOPS and CORVET are found widely throughout eukaryotes. The ciliate Tetrahymena thermophila is a unicellular organism with elaborate endolysosomal pathways. Curiously, Tetrahymena and related protozoa have lost HOPS. Tetrahymena encodes multiple paralogs of most CORVET subunits, assembled into six distinct hexameric complexes, including a distinct Vps8 subunit. Here we analyze the composition of these complexes immunoisolated by affinity capture using the Vps8-FLAG paralogs as bait.

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