Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Next Generation Sequencing Facilitates Quantitative Analysis of Col1a2+ stromal cells sorted from Col1a2-creERT Bmpr1a and ctrl mice

ABSTRACT: Next Generation Sequencing Facilitates Quantitative Analysis of Col1a2+ stromal cells sorted from Col1a2-creERT Bmpr1a and ctrl mice

PROVIDER: PRJNA1207509 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Next Generation Sequencing Facilitates Quantitative Analysis of Col1a2+ stromal cells sorted from Col1a2-creERT;Bmpr1a and ctrl mice

Project description:We had one goal to perform this study: transcriptome of Col1a2+ stromal cells sorted from Col1a2-creERT;Bmpr1a and ctrl mice

2025-07-31 | GSE286027 | GEO

Next Generation Sequencing Facilitates Quantitative Analysis of Epithelial cells sorted from Col1a2-creERT;Bmpr1a and ctrl mice

Project description:We had one goal to perform this study: transcriptome of Epithelial cells sorted from Col1a2-creERT;Bmpr1a and ctrl mice

2025-07-31 | GSE286383 | GEO

Next Generation Sequencing Facilitates Quantitative Analysis of keratocytes sorted from Prrx1-creERT;Ptch1 and ctrl mice

Project description:We had one goal to perform this study: transcriptome of keratocytes sorted from Prrx1-creERT;Ptch1 and ctrl mice

2025-12-31 | GSE290613 | GEO

Next Generation Sequencing Facilitates Quantitative Analysis of Epithelial cells sorted from Col1a2-creERT Bmpr1a and ctrl mice

Project description:Next Generation Sequencing Facilitates Quantitative Analysis of Epithelial cells sorted from Col1a2-creERT Bmpr1a and ctrl mice

| PRJNA1209037 | ENA

Next Generation Sequencing Facilitates Quantitative Analysis of Epithelial cells sorted from Prrx1-creERT;Ptch1 and ctrl mice

Project description:We had one goal to perform this study: transcriptome of Epithelial cells sorted from Prrx1-creERT;Ptch1 and ctrl mice

2025-12-31 | GSE290490 | GEO

Next Generation Sequencing Facilitates Quantitative Analysis of keratocytes sorted from Prrx1-creERT Ptch1 and ctrl mice

Project description:Next Generation Sequencing Facilitates Quantitative Analysis of keratocytes sorted from Prrx1-creERT Ptch1 and ctrl mice

| PRJNA1229009 | ENA

Next Generation Sequencing Facilitates Quantitative Analysis of Epithelial cells sorted from Prrx1-creERT Ptch1 and ctrl mice

Project description:Next Generation Sequencing Facilitates Quantitative Analysis of Epithelial cells sorted from Prrx1-creERT Ptch1 and ctrl mice

| PRJNA1228255 | ENA

Hormone-responsive Bmpr1a maintains myoepithelial integrity during pregnancy

Project description:Myoepithelial and luminal cells synergistically expand in the mammary gland during pregnancy, and this process is precisely governed by hormone-related signaling pathways. The BMP signaling pathway is now known to play crucial roles in all organ systems. However, the functions of BMP signaling in the mammary gland remain unclear. Here, we found that Bmpr1a is upregulated by hormone-induced Sp1 at pregnancy. Using a doxycycline (Dox)-inducible Bmpr1a conditional knockout mouse model, we demonstrated that loss of Bmpr1a results in compromised myoepithelial integrity, reduced mammary stem cells and precocious alveolar differentiation during pregnancy. Mechanistically, Bmpr1a regulates the expression of p63 and Slug, two key regulators of myoepithelial maintenance, through pSmad1/5-Smad4 complexes, and consequently activate P-cadherin during pregnancy. Collectively, these findings identify a novel role of BMP signaling in maintaining the identity of myoepithelial cells and suppressing precocious alveolar formation.

2021-03-05 | GSE164550 | GEO

Next-generation RNA Sequencing and Transcriptome Comparison of Mouse Wild Type and Mesenchymal Bmpr1a conditional knockout lungs of E15.5

Project description:Lung mesenchymal knockout of Bmpr1a will lead to lung malformation, including impaired lung branching and cystic lesion. In order to understand the underlying mechanisms, total RNA of wild type and mesenchymal Bmpr1a knockout lungs were isolated and sequenced using the next-generation RNA sequencing technique.

2024-04-01 | GSE97946 | GEO

Next Generation Sequencing Facilitates Quantitative Analysis of distal part of the auricle from three Prrx1-CreERT;Bmpr1af/f and age- and gender-matched control mice.

Project description:We had one goal to perform this study: Analysis of distal part of the auricle from three Prrx1-CreERT;Bmpr1af/f and age- and gender-matched control mice.

2024-04-09 | GSE240126 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data