Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Dibamus cf. smithi (Smith's blind skink) genome, rDibSmi1, sequence data

PROVIDER: PRJNA1208564 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR31946005_subreads.fastq.gz	Fastqsanger.gz
	SRR31946006_subreads.fastq.gz	Fastqsanger.gz
	SRR31946007_subreads.fastq.gz	Fastqsanger.gz
	SRR31946008_subreads.fastq.gz	Fastqsanger.gz
	SRR31946009_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 6

Similar Datasets

Project description:Dibamus cf. smithi (Smith's blind skink) genome, rDibSmi1

| PRJNA1195036 | ENA

Dibamus cf. smithi isolate:rDibSmi1

Project description:Dibamus cf. smithi (Smith's blind skink) genome, rDibSmi1, haplotype 1

| PRJNA1190889 | ENA

Dibamus cf. smithi isolate:rDibSmi1

Project description:Dibamus cf. smithi (Smith's blind skink) genome, rDibSmi1, haplotype 2

| PRJNA1190890 | ENA

Dibamus cf. smithi

Project description:Dibamus cf. smithi overview

| PRJNA1202333 | ENA

Project description:XX/XY sex chromosomes in the blind lizard Dibamus deharvengi

| PRJNA893868 | ENA

Project description:Tiliqua scincoides (blue-tongue skink) genome, rTilSci1, sequence data

| PRJNA1139171 | ENA

miRNA repertoires of ex-vivo bronchial, nasal, and polyps cells cultured from healthy and CF donors

Project description:Cystic fibrosis (CF), a genetic disorder, is characterized by chronic lung disease. Small non-coding RNAs are key regulators of gene expression and participate in various processes, which are dysregulated in CF; however, they remain poorly studied. Here, we determined the complete microRNAs (miRNAs) expression pattern in three CF ex-vivo models. The miRNA profiles of air-liquid interface cultures of airway epithelia (bronchi, nasal cells, and nasal polyps) samples from patients with CF and non-CF controls were obtained by deep sequencing. Compared with non-CF controls, several miRNAs were deregulated in CF samples, for instance miR-181a-5p and the miR-449 family were upregulated. Moreover, mature miRNAs often showed variations (i.e., isomiRs) relative to their reference sequence, such as miR-101, suggesting that miRNAs consist of heterogeneous repertoires of multiple isoforms with different effects on gene expression. Analysis of miR-181a-5p and miR-101-3p roles indicated that they regulate the expression of WISP1, a key component of cell proliferation/migration programs. We showed that miR-101 and miR-181a-5p participated in aberrant recapitulation of wound healing programs by controlling WISP1 mRNA and protein level. Our miRNA expression data bring new insights into CF physiopathology and define new potential therapeutic targets in CF

2020-10-21 | GSE159708 | GEO

Abronia smithi

Project description:Abronia smithi

| PRJNA1270674 | ENA

Turdus smithi strain:NA

Project description:Turdus smithi

| PRJNA969656 | ENA

Project description:Target capture data for Australian skink lizards

| PRJNA1175741 | ENA