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Single-cell landscape analysis reveals distinct regression trajectories and novel prognostic biomarkers in primary neuroblastoma

ABSTRACT: Single-cell landscape analysis reveals distinct regression trajectories and novel prognostic biomarkers in primary neuroblastoma

PROVIDER: PRJNA1212194 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR32039612_1.fastq.gz	Fastqsanger.gz
	SRR32039612_2.fastq.gz	Fastqsanger.gz
	SRR32039613_1.fastq.gz	Fastqsanger.gz
	SRR32039613_2.fastq.gz	Fastqsanger.gz
	SRR32039614_1.fastq.gz	Fastqsanger.gz

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Single-cell landscape analysis reveals distinct regression trajectories and novel prognostic biomarkers in primary neuroblastoma

Project description:Neuroblastoma (NB) is the most common extracranial malignant solid tumor in children, and its clinical manifestations and prognosis vary greatly. NB has a unique ability to spontaneously differentiate and regress, which provides potential directions for therapeutic interventions. To investigate the heterogeneity of tumors, we performed single-cell transcriptome sequencing on 19 tumor samples and 3 adrenal tissue samples, including 2 cases of familial neuroblastoma.

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