Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Galactose changed the transcriptome of endometrial epithelial cells after E. coli infection

ABSTRACT: Galactose changed the transcriptome of endometrial epithelial cells after E. coli infection

PROVIDER: PRJNA1213048 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR32052108_1.fastq.gz	Fastqsanger.gz
	SRR32052108_2.fastq.gz	Fastqsanger.gz
	SRR32052109_1.fastq.gz	Fastqsanger.gz
	SRR32052109_2.fastq.gz	Fastqsanger.gz
	SRR32052110_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Galactose changed the transcriptome of endometrial epithelial cells after E. coli infection

Project description:To elucidate the mechanism of galactose preventing endometritis, we treated mice with or without galactose and subsequently employed flow sorting to isolate endometrial epithelial cells.

2025-06-19 | GSE287462 | GEO

Progesterone inhibits epithelial-to-mesenchymal transition in endometrial cancer

Project description:This SuperSeries is composed of the following subset Series: GSE29435: Progesterone inhibits epithelial-to-mesenchymal transition in endometrial cancer: cell line data GSE29436: Progesterone inhibits epithelial-to-mesenchymal transition in endometrial cancer: patient data Refer to individual Series

2012-01-26 | E-GEOD-29437 | biostudies-arrayexpress

Gene expression is altered after infection with E. coli in endometrial organoids

Project description:We used human endometrium-derived epithelial cells to construct endometrial epithelial organoids, which were divided into two groups, the control group and the experimental group. The organoids in the experimental group were infected with Escherichia coli to explore the changes in gene expression before and after infection

2025-03-19 | GSE283460 | GEO

Progesterone signaling in endometrial epithelial organoids

Project description:Progesterone signaling in endometrial epithelial organoids

| PRJNA826845 | ENA

Endometrial epithelial Arid1a is essential in early pregnancy

Project description:Endometrial epithelial Arid1a is necessary for normal gene expression and maintenance of a receptive endometrium at pre-implantation stage in mice. We used RNA-sequencing to determine the differences in uterine gene expression resulting from deletion of endometrial epithelial Arid1a.

2022-03-01 | GSE196489 | GEO

SECRETORY PROTEOMIC RESPONSES OF ENDOMETRIAL EPITHELIAL CELLS TO TROPHOBLAST DERIVED EXTRACELLULAR VESICLES

Project description:Synchronized cross talk between embryo and endometrium during pre-implantation period is critical for establishment of pregnancy. Extracellular vesicels(EVs) of both embryo and endometrial origin are known to be integral in regulating embryo maternal communication during this time. However, exact molecular signalling pathways or factors that regulate the embryo endometrial communication during pre-conception period remains elusive. Here in this study extracellular vesicles from trophoblast cells were shown to modulate endometrial epithelial cell secretome in favour of embryo implantation and embryo development.

2023-10-24 | PXD040311 | Pride

Engraftment of self-renewing endometrial epithelial organoids promotes endometrial regeneration by differentiating into functional glands in rats

Project description:Extensive trauma disrupts endometrial regeneration by diminishing endometrial stem or progenitor cells. Endometrial epithelial organoids (EEOs) are used for endometrial regeneration. However, how EEOs repair injured endometrial tissues and their advantages over bone marrow mesenchymal stem cells (BMSCs) are unclear. This study explored whether EEOs surpass BMSCs to repair injured endometrium and examined whether endometrial restoration involves integrating EEOs into the endometrial tissue of the recipient. Rat EEOs (rEEOs) mimicking the features of the rat endometrium were developed. An endometrial injury rat model was used to compare the effects of rEEOs and rat BMSCs (rBMSCs) on endometrial regeneration and reproductive recovery. Bulk RNA-sequencing analysis was conducted to investigate the capacity of rEEOs for endometrial regeneration and identify discrepancies between rEEOs and rBMSCs. Green fluorescent protein (GFP)-labeled rEEOs or red fluorescent protein-labeled rBMSCs were transplanted to track the transplanted cells in vivo. Fertility recovery in rats transplanted with rEEOs was more comparable to that of normal rats than in rBMSC-treated rats. rEEOs had a high concentration of endometrial epithelial stem or progenitor cells and secreted vascular endothelial growth factor-A to promote endometrial neovascularization. Cells from GFP-labeled rEEOs integrated and differentiated into functional glands within the injured endometrium. Transplanting EEOs restored the morphology and function of severe endometrial injury better than BMSC transplantation. EEO cells repair the endometrium by differentiating into functional glandular epithelial cells. These findings offer preclinical evidence supporting in vitro expansion and transplanting of EEOs as promising approaches to restore fertility in women with insufficient endometrial regeneration.

2024-11-29 | GSE269747 | GEO

Transcriptomic effects of miR-30d transient over-expression in human endometrial epithelial cells.

Project description:microRNAs are essential regulators of gene expression. This work explores the transcriptomic effects of has-miR-30d in endometrial epithelial cells which was reported to be up-regulated during human endometrial receptivity. primary endometrial epithelial cells derived from four different endometrial biopsies taken on LH+0 were transiently transfected with miRNAs for 72 hours under two conditions (four scramble, four miR-30d mimic) and were evaluated for mRNA expression with Agilent’s gene expression microarray. A set of differentially expressed mRNAs were validated by qPCR.

2014-02-03 | E-GEOD-46721 | biostudies-arrayexpress

Transcriptome profiling of endometrial biopsies inflammatory response to Chlamydia trachomatis genital tract infection

Project description:Chlamydia trachomatis is an obligate intracellular Gram-negative bacterium that frequently causes an asymptomatic genital tract infection, gradually cleared by host immunity Transcriptome profiles were made of endometrial tissue from women with or without genital tract C. trachomatis infection, to characterize host responses to infection. Profiles showed that infection polarized host defense toward Type 2 immune responses. Responses included fibrin deposition, enhanced wound repair, and tissue remodeling. Trans-cervical endometrial biopsy specimens were collected from 10 women with no identified upper or lower genital tract infection and 12 women with C. trachomatis endometrial infection.

2013-03-01 | E-GEOD-41075 | biostudies-arrayexpress

SSEA-1+ and SSEA-1- endometrial epithelial cells

Project description:SSEA-1+ endometrial epithelial cells (EECs) assume the postulated stem progenitor cell niche within the human endometrium. Previous studies have demonstrated isolated SSEA-1+ cells to have a higher capacity to generate organoids in a 3D matrix, have lower steroid hormone expression and higher telomerase activity with longer telomere lengths. To further explore this we conducted transcriptional profiling comparing human SSEA-1 enriched and depleted endometrial epithelial cells from eight individuals.

2025-05-07 | GSE280323 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data