Mus musculus
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA122815 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:This SuperSeries is composed of the following subset Series: GSE14559: Timed induction of 50 transcription factors in ES cells reveals a common mechanism to initiate differentiations GSE14586: Cdx2 Binding Sites On Cdx2 Expressing ES Cells GSE16148: Timed induction of 10 transcription factors - ES time series data Refer to individual Series
2009-09-30 | E-GEOD-16375 | biostudies-arrayexpress
Project description:Transcription profiling time series IFH1 overexpression by galactose induction in S. cerevisiae
2015-09-08 | E-GEOD-1934 | ExpressionAtlas
Project description:Transcription profiling time series of human mesenchymal stem cells after induction of differentiation
2025-01-22 | E-MEXP-858 | ExpressionAtlas
Project description:Timed induction of 50 transcription factors in ES cells reveals a common mechanism to initiate differentiations
| PRJNA123179 | ENA
Project description:Transcription profiling time series of mouse embryonic chondrocyte differentiation
2014-08-15 | E-GEOD-2154 | ExpressionAtlas
Project description:Transcription profiling of rats with colitis induced with trinitrobenzene sulfonate - time series
2015-10-22 | E-MEXP-873 | ExpressionAtlas
Project description:Controlled induction of 49 transcription factors in transgenic mouse ES cell lines
| PRJNA293862 | ENA
Project description:Transcription profiling of HD R6/1 transgenic mouse line brain hemispheres, time series
2015-09-28 | E-GEOD-3621 | ExpressionAtlas
Project description:To decipher the structure and behaviors of the transcription factor (TF) network, we created 50 permanent mouse ES cell lines, in each of which one of the 50 transcription factors tagged with FLAG, is inserted into the doxycycline (dox)-repressible ROSA26 locus. We have obtained time series data for 10 of the transcripts at 24h,48h and 72hr. Expression profiling reveals Cdx2 as the most potent inducer of transcriptome perturbation in ES cells, followed by Esx1, Sox9, Tcf3, Klf4, and Gata3. Immunoprecipitation (IP) with a FLAG-antibody in Cdx2-induced ES cells, identifies NuRD in CDX2-associated protein complexes; and chromatin-IP-sequencing identifies CDX2-binding sites predominantly in genes up-regulated by CDX2. Compendium analyses of Cdx2- and the other TF-inducible ES cells suggest a central role of the POU5F1/SOX2/NANOG protein complex in a swift-acting control mechanism to down-regulate a common set of genes at the beginning of multi-lineage ES cell differentiations. These ES cell lines will be a valuable resource to study biological networks in ES cells and mice. Keywords: dose response design,genetic modification design,individual genetic characteristic design,reference design,replicate design,time series design
2009-10-01 | GSE16148 | GEO
Project description:Transcription profiling by array time series of human MCF7 breast cancer cells treated with estradiol
2025-01-16 | E-GEOD-11352 | ExpressionAtlas