Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Sequencing of Goose Fowl Adenoidal Lymphoid Nodule (Bursa of Fabricius)

PROVIDER: PRJNA1229167 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR32541050_1.fastq.gz	Fastqsanger.gz
	SRR32541050_2.fastq.gz	Fastqsanger.gz
	SRR32541051_1.fastq.gz	Fastqsanger.gz
	SRR32541051_2.fastq.gz	Fastqsanger.gz
	SRR32541052_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Comparative proteomic analysis revealed the differential responses to novel duck reovirus infection in the bursa of Fabricius of Cairna moschata

Project description:Duck reovirus (DRV) is well-studied aquatic bird virus belonging to the Orthoreovirus genus of the Reoviridae family. The bursa of Fabricius is an immunologically organ against virus invasion. However, the responses of the bursa of Fabricius of Cairna moschata to DRV infection are largely unknown. To investigate the immune responses, the proteomes from the control and two DRV strain infected samples (NH and DJ) were compared. In total, 7075 protein were identified, of which 5625 protein were quantified. A number of differentially expressed proteins (DEPs), including 210 DEPs under the HN10 infection and 55 DEPs under the JD10 infection, were identified. Protein network analysis showed that the DEPs enriched in the serine protease system and the innate immune response clusters. For the serine protease systems, coagulation factor IX, three chains of fibrinogen, and complement C8, C5, and C2s were significantly up-regulated, suggesting that the serine protease-mediated immune might be involved in the responses to the HN10 infection. For the innate and adaptive immune system, RIG-I, MDA5, MAPK20, and IRF3 were significantly up-regulated, indicating their important role in the reorganization of invaded virus. Furthermore, the DEPs among different visceral organs (liver, spleen, and the bursa of Fabricius) were compared. coagulation factor IX was significantly up-regulated in the bursa of fabricius, not in the liver and spleen samples, suggesting an important role of the bursa of fabricius in antivirus. Our data may give a comprehensive resource for investigating the regulation mechanism involved in the responses of the bursa of Fabricius of duck to the DRV infections.

2022-08-12 | PXD025093 | Pride

Characterization of the transcriptome profile of bursa of Fabricius infected by Muscovy duck reovirus in muscovy ducklings

Project description:Whole transcriptome sequencing was carried on to investigate the different response of bursa of Fabricius of ducklings to HN10 (virulent NDRV) and JDm10 (naturally attenuated NDRV).

2022-08-29 | E-MTAB-12115 | biostudies-arrayexpress

Transcription profiling by array of differential gene expression in chicken primary B cells infected ex vivo with attenuated and very virulent strains of infectious bursal disease virus (IBDV)

Project description:Infectious bursal disease virus (IBDV) belongs to the family Birnaviridae and is economically important to the poultry industry worldwide. IBDV infects B cells in the bursa of Fabricius (BF), which can cause severe immunosuppression and mortality in young chickens. Earlier studies have shown that strains of IBDV lose their virulence potential after serial passage in non-B lymphoid cells, for reasons that are poorly understood. This study aimed to investigate the gene expression profiles of one cell-culture adapted attenuated IBDV strain (D78) and one very virulent IBDV strain (UK661) in chicken primary B cells cultured ex vivo from the bursa of Fabricius. The viruses were studied in B cells over 48h and their gene expression was initially evaluated with qPCR. The mRNA was isolated from the cells at 18 hours post-infection and screened with Affymetrix microarrays in triplicate. The study included mock controls which were conducted in triplicate.

2017-11-01 | E-MTAB-5947 | biostudies-arrayexpress

Changes in miRNA expression during infection with strong IBDV strains

Project description:In our previous studies, we found that the bursae of Fabricius in chickens infected with IBDV were severely atrophied and resulted in immune suppression in the chickens. Therefore, we decided to detect the differential expression of miRNA in chickens infected with IBDV by RNA-seq. We then used the data obtained from bursa of Fabricius RNA-seq for gene expression profiling. Our ultimate goal is to study the regulatory mechanisms of host mirnas on IBDV viruses or cells.

2023-02-10 | GSE224123 | GEO

A survey of gene expression in adult chicken tissues using a chicken 20K oligonucleotide microarray

Project description:Transcriptional profiling of eight normal adult chicken tissues in 10-week old brown (lohmann brown) hens, the eight tissues include brain, bursa of Fabricius, jejunum, kidney, liver, lung, spleen, thymus. Keywords: normal chicken tissues, transcriptional profiling.

2010-03-08 | GSE17108 | GEO

Gene expression of bursa fabricius of Thai indigenous chicken breeds

Project description:Analysis of gene expression of Bursa of Fabricius samples of 3 male chickens of 6 breeds revealed differential expression of genes related to Ingenuity pathways immune cell trafficking, cell-mediated immune response, humoral immune response and infectious disease.

2018-12-31 | GSE107114 | GEO

Transcription profiling of bursa of Fabricius from genetically resistant and susceptible chickens infected with Infectious Bursal Disease Virus (IBDV)

Project description:We used a chicken immune-targeted gene array to analyse the differences in gene expression in the bursa of Fabricius from genetically resistant and susceptible animals infected with Infectious Bursal Disease Virus (IBDV).

2006-10-19 | E-MEXP-756 | biostudies-arrayexpress

RNA-seq of mRNAs from spleen and bursa of Fabricius of white leghorn chickens (specific pathogen-free)

Project description:We have used RNA-seq to examine mRNAs from chicken spleen and bursa of Fabricius of three different condition (non-immunized and non-heat-stressed (24 ± 1℃ for 3 h), immunized (Newcastle disease vaccine) and non-heat-stressed, and immunized and heat-stressed (36 ± 1℃ for 3 h)). To clarify how chicken immune systems responded to heat stress with and without immunization.

2018-12-01 | GSE93224 | GEO

Expression of known and predicted genes in tissues of Gallus gallus (chicken)

Project description:Expression of known and predicted genes in tissues of Gallus gallus (chicken) pooled from multiple healthy individuals. Two-colour experiments with two different tissues hybridized to each array. Each tissue is arrayed in replicate with dye swaps. Tissues: Bursa of Fabricius, Cerebellum, Cerebral cortex, Eye, Femur with bone marrow, Gallbladder, Gizzard, Heart, Intestine, Kidney, Liver, Lung, Muscle, Ovary, Oviduct, Skin, Spleen, Stomach, Testis, Thymus

2010-06-19 | E-GEOD-12974 | biostudies-arrayexpress

Gene expression data from maturing oocyte of chickens

Project description:In avian species, maternal blood immunoglobulin Y (IgY) is transferred to the egg yolks of maturing oocytes, but the mechanism underlying this transfer is unknown. IgY-deficient chickens were developed by removal of bursa of Fabricius (Bx group). Since DIG-labeled IgY uptake into egg yolk was approximately 2-fold higher in the Bx group than that of the control, upregulated genes in oocyte of the Bx group were determined to identify IgY receptor responsible for maternal blood IgY transfer by microarray analysis.

2019-07-23 | GSE134668 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data