Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Multi-omics analyses construct an inflammatory response based prognostic gene signature for cervical cancer and suggest tumor infiltrating monocytes subgroups as key players

ABSTRACT: Multi-omics analyses construct an inflammatory response based prognostic gene signature for cervical cancer and suggest tumor infiltrating monocytes subgroups as key players

PROVIDER: PRJNA1235690 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR32685108_1.fastq.gz	Fastqsanger.gz
	SRR32685108_2.fastq.gz	Fastqsanger.gz
	SRR32685109_1.fastq.gz	Fastqsanger.gz
	SRR32685109_2.fastq.gz	Fastqsanger.gz
	SRR32685110_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 46

Similar Datasets

Multi-omics analyses construct an inflammatory response based prognostic gene signature for cervical cancer and suggest tumor infiltrating monocytes subgroups as key players

Project description:A multi-gene model based on inflammatory response relevant genes was constructed for cervical cancer patients. The association of patients’ scores for the model and the characteristics of tumor microenvironment as well as patients’ predicted response to anti-cancer treatments was analyzed. Based on the single-cell RNA-sequencing (scRNA-seq) data, two tumor infiltrating monocytes (TIM) clusters were found to be associated with the inflammatory response in the tumor microenvironment. The tumour tissues of 23 cervical adenocarcinoma patients in our hospital were collected and bulk RNA-sequencing was carried out. The correlation of marker genes of the two TIM clusters and patients’ score of the multi-gene model was analyzed to validate the findings on the scRNA-seq data.

2025-05-15 | GSE291865 | GEO

Multi-omics analyses construct an inflammatory response based prognostic gene signature for cervical cancer and suggest tumor infiltrating monocytes subgroups as key players

Project description: Not available

| S-EPMC12127166 | biostudies-literature

Gene expression based profiling of pleomorphic xanthoastrocytoma highlights two prognostic subgroups

Project description:First comprehensive analysis highlighting distinct molecular subgroups of PXA. The DEGs between two clusters may potentially be used for developing histology independent classification scheme, prognostication and suggest prospective therapeutic targets

2021-12-14 | GSE168904 | GEO

Integrative Analysis Defines Distinct Prognostic Subgroups of Intrahepatic Cholangiocarcinoma

Project description:Intrahepatic cholangiocarcinoma (iCCA) is the second most common primary liver cancer. It is defined by cholangiocytic differentiation and has poor prognosis. Recently, epigenetic processes have been shown to play an important role in cholangiocarcinogenesis. We performed an integrative analysis on 52 iCCAs using both genetic and epigenetic data with a specific focus on DNA methylation components. We identified four major iCCA subgroups with widespread genomic and epigenomic differences and prognostic implications. Furthermore, our data suggest differences in the cell-of-origin of the iCCA subtypes.

2022-08-12 | GSE201241 | GEO

Medulloblastoma in adults: Cytogenetic phenotypes identify prognostic subgroups

Project description:Medulloblastoma in adults: Cytogenetic phenotypes identify prognostic subgroups

| PRJNA704366 | ENA

synthetic construct

Project description:synthetic construct

| PRJNA1455825 | ENA

Synthetic construct

Project description:Synthetic construct

| PRJNA260755 | ENA

synthetic construct

Project description:synthetic construct