Project description:The study was designed to test the global impact of negative supercoiling on gene expression in model archaeon T. kodakarensis. Exogenous wild type GyrA or GyrAY119F and wild type GyrB from Thermotoga maritima was expressed under the constitutive PhmtB promoter in T. kodakarensis cells.
Project description:Interventions: Gold Standard:the pathological biopsy results after resection of colorectal mass;Index test:elasticity score; strain ratio
Primary outcome(s): elasticity score;strain ratio;the pathological biopsy results after resection of colorectal mass
Study Design: Diagnostic test for accuracy