Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gut Clostridia

ABSTRACT: Genomic diversity of gut Clostridia

PROVIDER: PRJNA1241798 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR33196100_1.fastq.gz	Fastqsanger.gz
	SRR33196100_2.fastq.gz	Fastqsanger.gz
	SRR33196101_1.fastq.gz	Fastqsanger.gz
	SRR33196101_2.fastq.gz	Fastqsanger.gz
	SRR33196102_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 42

Similar Datasets

Clostridia bacterium

Project description:Clostridia bacterium overview

| PRJNA700747 | ENA

Effect of Clostridia strains on EAE clinical outcome as a therapeutic treatment

Project description:Researchers have induced an experimental model of multiple sclerosis [experimental autoimmune encephalomyelitis (EAE)] in mice to investigate the therapeutic effect of the oral treatment with selected Clostridia strains on the clinical outcome of EAE and its mechanisms of action

2021-09-15 | GSE155438 | GEO

Morphine treatment induces distinct changes in the gut microbiome at day 3 post treatment

Project description:Opioids such as morphine have many beneficial properties as analgesics, however, opioids may induce multiple adverse gastrointestinal symptoms. We have recently demonstrated that morphine treatment results in significant disruption in gut barrier function leading to increased translocation of gut commensal bacteria. However, it is unclear how opioids modulate the gut homeostasis. By using a mouse model of morphine treatment, we studied effects of morphine treatment on gut microbiome. We characterized phylogenetic profiles of gut microbes, and found a significant shift in the gut microbiome and increase of pathogenic bacteria following morphine treatment when compared to placebo. In the present study, wild type mice (C57BL/6J) were implanted with placebo, morphine pellets subcutaneously. Fecal matter were taken for bacterial 16s rDNA sequencing analysis at day 3 post treatment. A scatter plot based on an unweighted UniFrac distance matrics obtained from the sequences at OTU level with 97% similarity showed a distinct clustering of the community composition between the morphine and placebo treated groups. By using the chao1 index to evaluate alpha diversity (that is diversity within a group) and using unweighted UniFrac distance to evaluate beta diversity (that is diversity between groups, comparing microbial community based on compositional structures), we found that morphine treatment results in a significant decrease in alpha diversity and shift in fecal microbiome at day 3 post treatment compared to placebo treatment. Taxonomical analysis showed that morphine treatment results in a significant increase of potential pathogenic bacteria. Our study shed light on effects of morphine on the gut microbiome, and its role in the gut homeostasis.

2018-04-16 | E-MTAB-5546 | biostudies-arrayexpress

16S rRNA community profiling of the gut of the African Palm weevil

Project description:To explore the bacterial community profile of the gut of the African palm weevil and to identify the abundance and diversity of lignin degradation-associated bacteria in each gut segment.

2025-01-01 | E-MTAB-13719 | biostudies-arrayexpress

Clostridia bacterium

Project description:Clostridia bacterium Genome sequencing and assembly

| PRJNA644231 | ENA

Butyrate producing Soil Clostridia species

Project description:Soil clostridia species metabolism for butyrate production

2024-12-05 | MSV000096601 | MassIVE

Gut microbiome communication with the bone marrow regulates intestinal inflammation and susceptibility to amebiasis.

Project description:We discovered that colonization of the gut with the human bile acid 7'-dehydroxylating bacteria Clostridia scindens provided immunity to the parasite E. histolytica in a murine model, increased granulocyte monocyte progenitors, and that adoptive marrow transplant from C. scindens colonized mice into naive mice could recapitualte this protection.

2020-08-10 | GSE121503 | GEO

Clostridia

Project description:Endosymbiotic clostridia within the cells of protists in the termite guts

| PRJDB15329 | ENA

Clostridia bacterium JGI 000170CP_E03

Project description:Clostridia bacterium JGI 000170CP_E03 Genome sequencing

| PRJNA363908 | ENA

Clostridia bacterium JGI 000170CP_B08

Project description:Clostridia bacterium JGI 000170CP_B08 Genome sequencing

| PRJNA368428 | ENA